Results 191 to 200 of about 29,012,891 (356)

First-line treatment patterns and real-world survival outcomes in PD-L1-negative locally recurrent inoperable or metastatic triple-negative breast cancer in the United States. [PDF]

Breast Cancer Res Treat
Traina TA, Serra E, Bedard J, Levesque-Leroux M, Gagnon-Sanschagrin P, Guérin A, Guenther S, Joseph G, Guan V, Salcedo J.   +9 more
europepmc   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Real Option Applications to Information Security [PDF]

Real options present advantages over the standard discounting methods. In this paper we analyze them briefly and examine their potential applications on information security.
Pythagoras PETRATOS
core  

Prêt-à-Jouer: commercial videogames as ready-made human perception labs. [PDF]

Front Cognit
Munneke J, Anthony B, Corbett JE.
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Assessing agricultural policy incentives for Greek organic agriculture: A Real options approach [PDF]

The adoption of organic agriculture or livestock involves risk and uncertainty, and to overcome this, well designed schemes are required. Are the current support measures attractive for farmers who wish to convert to organic?
Tzouramani, Irene, Liontakis, Angelos E., Alexopoulos, George, Sintori, Alexandra   +3 more
core  

Current Gaps in Point-of-Care Ultrasound Supervision in Generalist Practice in Japan: A Nationwide Survey. [PDF]

J Gen Fam Med
Yamada T, Kimura T, Shigetomi K, Shinohara T, Ouchi S, Mabuchi S, Ichige H, Kameda T, Yoshino S, Kitano Y, Endo K, Okada K, Kamijo H, Takahashi H, Kusama T, Ishida T, Hashimoto M.   +16 more
europepmc   +1 more source

Real options analysis of investment in solar vs. wind energy: Diversification strategies under uncertain prices and costs

, 2018
Ardjan Gazheli, J. van den Bergh
semanticscholar   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Internalization and internationalization under copeting real options [PDF]

The theories of internalization and internationalization provide general factors of international market entry but are not precise about its timing. A model of waiting and growth options seizes the importance of flexibility to FDI decisions and centers ...
Fisch, Jan Hendrik
core