Results 201 to 210 of about 666,196 (263)

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Unmet needs in the care of patients with neuromyelitis optica spectrum disorder and myelin oligodendrocyte glycoprotein antibody associated disease: insights from Germany. [PDF]

Neurol Res Pract
Giglhuber K, Bertrand A, Zappe C, Kleiter I, Ayzenberg I, Berthele A, Neuromyelitis Optica Study Group (NEMOS).   +6 more
europepmc   +1 more source

Low Incidence of Relapses After Vaccination in Anti‐Aquaporin‐4 Antibody‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Patients with neuromyelitis optica spectrum disorder (NMOSD) may experience increased signs and symptoms of their underlying disease when vaccinated against meningococcal disease before receiving complement component 5 inhibitor therapies. This retrospective analysis indicated an overall low relapse incidence (mean [range], 3.3% [0.7%–10.6 ...
Sean J. Pittock, Jin Nakahara, Becky Parks, Kerstin Allen, Sami Fam   +4 more
wiley   +1 more source

Supporting Parental Decision-Making After Life-Limiting Fetal Diagnoses: The Role of Perinatal Hospice and the NOVA-L Decision Support System. [PDF]

Healthcare (Basel)
Dahò M.
europepmc   +1 more source

An intelligent computational framework combining neural networks with complex Pythagorean fuzzy FUCA for airspace capacity evaluation and traffic forecasting. [PDF]

Sci Rep
Huo D, Zhang S.
europepmc   +1 more source

Real-world treatment of hyperkalemia among patients in emergency department in China (POETRY-E): A study protocol for multicenter, prospective, observational study. [PDF]

J Int Med Res
Yangyang F, Yao W, Yili D, Miao G, Huadong Z, Xuezhong Y, Jun X, Zhaoxing T.   +7 more
europepmc   +1 more source

What if I needed help? Population preferences for first-line mental health treatments in the post-COVID time. [PDF]

Front Psychiatry
Voderholzer U, Wuttke EP, Zisler EM, Baumeister A, Jelinek L.   +4 more
europepmc   +1 more source

Benchmarking publicly accessible large language models for high-myopia multiple-choice question generation in digital ophthalmic education and public health training. [PDF]

Front Public Health
Jiang L, Jiang X, Wu W, Jiang F.
europepmc   +1 more source

User choice, hidden gems, and the quadratic horizon. [PDF]

PNAS Nexus
Chierichetti F, Giacchini M, Kumar R, Panconesi A, Tomkins A.   +4 more
europepmc   +1 more source