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Current Medical Science, 2022
Realgar is a traditional mineral Chinese medicine with antitumor effects, but it has high toxicity and low efficacy in its crude form. The purpose of this study was to optimize realgar to increase its efficacy and therapeutic potential.Crude realgar (CR) was mechanically ground to obtain nano-realgar (NR), and then nano-realgar processed products ...
Juan, Xi +5 more
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Realgar is a traditional mineral Chinese medicine with antitumor effects, but it has high toxicity and low efficacy in its crude form. The purpose of this study was to optimize realgar to increase its efficacy and therapeutic potential.Crude realgar (CR) was mechanically ground to obtain nano-realgar (NR), and then nano-realgar processed products ...
Juan, Xi +5 more
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Toxicokinetics and tissue distribution study of arsenic in realgar
China Journal of Chinese Materia Medica, 2010To study the toxicokinetics and tissue distribution of total arsenic after giving different doses realgar to rats.The concentration of arsenic in blood, urine and main organs were determined after single oral administration of 3.738, 1.869, 0.935 g x kg(-1) realgar in rats.The distribution half life (t(1/2 alpha)) and elimination half life (t(1/2 beta))
Juan, Zhang, Yishan, Tang, Qide, Liu
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The Vaporization of Realgar, As4 S 4
Journal of The Electrochemical Society, 1983The vaporization behavior of has been investigated by mass spectrometry and mass‐loss torsion‐effusion. The results of these studies indicate that the primary constituent of the vapor above crystalline is molecular , but that minor amounts of , , , , , and are also present. The enthalpy and entropy of vaporization at 450 K are and , respectively.
R. D. Brittain +2 more
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Development of Realgar Nanotherapeutics for Cancer Treatments
2020Realgar is a kind of mineral drug and has a long history of medical use in Chinese medicine. The active component of realgar is As4S4 and can be orally administrated. In past decades, several traditional Chinese prescriptions containing realgar has showed certain clinical effects in the treatment of some hematologic malignancies.
Tao Wang, Haiyan Xu
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[Study on water processing conditions of Realgar].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2009To optimize the water processing (shui-fei) condition of Realgar.The processing conditions were optimized by L9 (3)4 orthogonal design with three factors as water dose, process times and dryness temperature. The content of dissolved arsenic As(III) in Realgar was tested by High Performance Liquid Chromatography-hydride generation on-line coupled with ...
Hong, Jiang +6 more
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Zeitschrift für anorganische und allgemeine Chemie, 1969
AbstractBei der Umsetzung von Realgar, As4S4, in N‐Methylaminoäthanol mit Piperidin oder Hexamethylenimin entstehen ein Piperidinium‐ bzw. Hexamethyleniminiumsalz mit dem Anion As4S. Durch doppelte Umsetzung mit Schwermetallsalzen gelingt es, Verbindungen der annähernden Zusammensetzung PbAs4S6 und HgAs4S6 zu erhalten. Das den neuen Thiosalzen zugrunde
Wilhelm Lauer +2 more
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AbstractBei der Umsetzung von Realgar, As4S4, in N‐Methylaminoäthanol mit Piperidin oder Hexamethylenimin entstehen ein Piperidinium‐ bzw. Hexamethyleniminiumsalz mit dem Anion As4S. Durch doppelte Umsetzung mit Schwermetallsalzen gelingt es, Verbindungen der annähernden Zusammensetzung PbAs4S6 und HgAs4S6 zu erhalten. Das den neuen Thiosalzen zugrunde
Wilhelm Lauer +2 more
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[Identification of realgar and arsenopyrite and their sublimates].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2001In this paper, two traditional Chinese medicinal minerals realgar and arsenopyrite, as well as their sublimates are identified in their nature, physical and optical properties, chemical compositions and trace elements. The result has shown that there are marked differences among realgar, arsenopyrite and their sublimates, and it should be particularly ...
F, Li, L, Li, Y, Han
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Orpiment and Realgar in Chinese Technology and Tradition
Journal of the American Oriental Society, 1955AMONG THE MINERAL PIGMENTS known to the Chinese since classical times the most important are the yellows,a the verditers,b ochreC and vermilion.d The present paper is devoted to the members of the class of mineral yellows in their material and spiritual relations throughout Chinese history.
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Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2018
To investigate the effect of clinical dose of Realgar-Indigo Naturais formula (RIF) and large-dose of Realgar on main drug-metabolizing enzymes CYP450s of rat liver, as well as its regulatory effect on mRNA expression. Wistar rats were administrated orally with tested drugs for 14 days.
Huan-Hua, Xu +8 more
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To investigate the effect of clinical dose of Realgar-Indigo Naturais formula (RIF) and large-dose of Realgar on main drug-metabolizing enzymes CYP450s of rat liver, as well as its regulatory effect on mRNA expression. Wistar rats were administrated orally with tested drugs for 14 days.
Huan-Hua, Xu +8 more
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The crystal structure of realgar
Acta Crystallographica, 1952T. Ito, N. Morimoto, R. Sadanaga
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