Results 111 to 120 of about 577,749 (308)
Comparison between the effects of group-based acceptance and commitment therapy and group-based reality therapy on work-family conflict & psychological well-being of married female staffs [PDF]
مجله علمی دانشگاه علوم پزشکی کردستان, 2019 Background and Aim: Administration of the therapy protocols can increase psychological well-being with resultant decrease in the work-family conflict. The purpose of this study was to make a comparison between the effects of group-based acceptance and ...
Hajikaram A, Ghamari M, Amiri Majd M
doaj
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Gene therapy: Myth or reality?
Comptes Rendus. Biologies, 2016 Gene therapy has become a reality, although still a fragile one. Clinical benefit has been achieved over the last 17 years in a limited number of medical conditions for which pathophysiological studies determined that they were favorable settings. They include inherited disorders of the immune system, leukodystrophies, possibly hemoglobinopathies ...
openaire +2 more sources
Trunk motion visual feedback during walking improves dynamic balance in older adults: Assessor blinded randomized controlled trial. [PDF]
, 2018 BACKGROUND: Virtual reality and augmented feedback have become more prevalent as training methods to improve balance. Few reports exist on the benefits of providing trunk motion visual feedback (VFB) during treadmill walking, and most of those reports ...
Anson, Eric +6 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
The Effectiveness of Reality Therapy Training on Marital Engagement and Marital Engagement in Married Students in Azad University [PDF]
پژوهش در نظامهای آموزشی, 2018 The purpose of this study was to investigate the effectiveness of therapeutic reality on increasing the marital status of marital students. The research method was semi-experimental. In this research, the statistical society included all married students
Abotaleb Seadatee shamir +2 more
doaj
Immersive Virtual Reality for the Management of Pain in Community-Dwelling Older Adults. [PDF]
, 2018 Immersive virtual reality (VR) can provide a high level of engagement and distraction analgesia to address pain. However, community-based applications of this technology for older adults have not been studied.
Benham, Sara +2 more
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source