Results 31 to 40 of about 117,304 (262)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The Effectiveness of Group Reality Therapy in the Development of Emotional Autonomy and Positive and Negative Affect in Students [PDF]

خانواده و پژوهش, 2022
Autonomy and positive and negative affect are among the most significant factors affecting the quality of life and academic achievement of students. Accordingly, this study aimed to examine the effectiveness of group reality therapy in the development of
N. Mikelani, H. Rezaee Jamalou’ee, Ph.D., M. Taheri, Ph.D., I. Saeedi, H. Gholami   +4 more
doaj  

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

The Effectiveness of Group Reality Therapy on the Psychological Capital and Responsibility among Children of Divorce

Salāmat-i ijtimā̒ī, 2020
Background and Objective: The growth of divorce in recent years has increased the number of children of divorce and the problems and issues arising from divorce in this sensitive period of development can be strongly influenced by psychological and ...
Abbas Sadeghian, Mohammad-Kazem Fakhri, Ramezan Hasanzadeh   +2 more
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The effect of reality therapy group counseling on pregnant women’s sexual function: An interventional study [PDF]

حیات
Background & Aim: Pregnant women experience physiological changes and may fear harming themselves or their fetus, leading some to avoid sexual intercourse during pregnancy. This avoidance can lead to sexual health issues.
Fatemeh Bahadori, Mahtab Attarha, Fatemeh Mehrabi Rezveh   +2 more
doaj  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

The Effectiveness of WDEP Reality Counseling in Reducing Social Comparison Among Students

Al-Musyrif
The excessive use of social media among adolescents has triggered the phenomenon of social comparison, which has a negative impact on mental health and academic performance.
Nuria Nurul Jannah, Weni Kurnia Rahmawati, Nailul Fauziyah, Henny Christine Mamahit   +3 more
doaj   +1 more source

A comparative analysis of the effectiveness of reality therapy and cognitive behavioral therapy training on the development of preventive and interventive self-control in incompatible couples [PDF]

Journal of Research in Psychopathology
The purpose of this study is to provide a comparative analysis of teaching reality therapy and cognitive behavioral therapy on the development of preventive and interventive self-control in incompatible couples.
Leila Mahmoudian, Firoozeh Zangane Motlagh, Mahdi Dehestani   +2 more
doaj   +1 more source