Results 121 to 130 of about 97,145 (309)

Not Missing the Notch: Detection Challenges of Juxtamembrane NOTCH1 Variant Detection in T‐Cell Acute Lymphoblastic Leukemia

Journal of Clinical Laboratory Analysis, EarlyView.
ABSTRACT Background Activating mutations in NOTCH1 are frequent in T‐cell acute lymphoblastic leukemia (T‐ALL) and, in the absence of alterations in RAS or PTEN, are associated with favorable prognosis. Besides classical heterodimerization and PEST domain mutations, juxtamembrane internal tandem duplications (JME‐ITDs) represent a third class of ...
Francisco Beas, Stephan Hutter, Ferran Balbastre‐Úbeda, Sandra Novoa‐Jáuregui, Maria Gabarrós‐Subirà, Eulalia Genescà, Petri Pölönen, Torsten Haferlach, Andrés Jerez   +8 more
wiley   +1 more source

Bridging Bystander Intervention and Workplace Inclusion: The Critical Role of Perceived Fairness, Support, and Safety

Journal of Organizational Behavior, EarlyView.
ABSTRACT Bystander intervention is widely assumed to foster workplace inclusion, yet no studies have directly examined this relationship. Through abductive qualitative analysis of 53 interviews across two contrasting organisations—a consulting firm and a remote mine site—we investigate how bystander intervention relates to workplace inclusion for ...
Laura Jennings, Kun Zhao, Liam Smith, Denise Goodwin, Nicholas Faulkner   +4 more
wiley   +1 more source

Ivermectin, A Reanalysis of the Data

American Journal of Therapeutics, 2021
Paul E. Marik, Pierre Kory
openaire   +3 more sources

Sampling Biases in Daily Average Temperatures From Greenland Climate Records

International Journal of Climatology, EarlyView.
Biases are introduced in the calculation of daily average temperatures due to uneven sampling times for the investigated weather station network in Greenland. The figure shows the network, an example of a daily temperature cycle with daily averages based on all or only two observations and an overview of how the number of observations per day changes ...
Dina Rapp, Bo M. Vinther, Jacob L. Høyer, Caroline D. Jensen, Johan H. Scheller   +4 more
wiley   +1 more source

Compound heterozygous missense and intronic variants in B9D1 contribute to a recurrent Meckel syndrome pedigree

Frontiers in Genetics
BackgroundMeckel syndrome (MKS) is an embryonically lethal ciliopathy with severe clinical manifestations, including defects of the central nervous system, bilateral renal cystic dysplasia, and postaxial polydactyly.
Huining Jing, Huining Jing, Bocheng Xu, Bocheng Xu, Hao Wang, Hao Wang, Shanling Liu, Shanling Liu, He Wang, He Wang, Jingqun Mai, Jingqun Mai, Wencong Yao, Wencong Yao, Zhu Zhang, Zhu Zhang   +15 more
doaj   +1 more source

Projected Intensification of Hydroclimatic Extremes in Rio Grande do Norte, Brazil, Under CMIP6 Scenarios

International Journal of Climatology, EarlyView.
The graphical abstract presents observed (1963–2023) and projected changes in hydroclimatic extremes in Rio Grande do Norte, Brazil. It integrates dry‐spell duration (CDD) and extreme precipitation (R95pTOT) using CMIP6 multimodel ensembles under SSP1‐2.6, SSP2‐4.5, and SSP5‐8.5.
Daris Correia dos Santos
wiley   +1 more source

How Well Is Surface Diurnal Temperature Range Represented by Observations at 2‐m Level

International Journal of Climatology, EarlyView.
We demonstrate that geostationary satellites depict well the Diurnal Temperature Range (DTR) in the US but differ from information at 2 m level from model outputs. Upper: mean diurnal temperature range (DTR) using GOES‐E based land surface temperature (LST) for January (left) and July (right) during 2004–2009. Lower: mean diurnal temperature range (DTR)
Rachel T. Pinker, Wen Chen, Yingtao Ma, Bin Fang, Venkataraman Lakshmi   +4 more
wiley   +1 more source

Modeling of Biologically Effective Daily Radiant Exposures over Europe from Space Using SEVIRI Measurements and MERRA-2 Reanalysis

Remote Sensing
Ultraviolet solar radiation at the Earth’s surface significantly impacts both human health and ecosystems. A biologically effective daily radiant exposure (BEDRE) model is proposed for various biological processes with an analytical formula for its ...
Agnieszka Czerwińska, Janusz Krzyścin
doaj   +1 more source

Performance Evaluation of the MPAS Model in Simulating Southeast Asian Rainfall Characteristics

International Journal of Climatology, EarlyView.
This study evaluates the performance of the Model for Prediction Across Scales–Atmosphere (MPAS) in reproducing key rainfall characteristics over Southeast Asia (SEA) during 2000–2020, using the MSWEP dataset as reference. MPAS realistically captures the observed meridional rainfall gradient, with higher rainfall in the south and lower in the north, as
Nguyen Thanh Hung, Alugula Boyaj, Srivatsan V. Raghavan, Nguyen Ngoc Son, Bhenjamin Jordan Ona   +4 more
wiley   +1 more source

Seasonal Characteristics of Mesoscale Convective Systems Over the Philippines

International Journal of Climatology, EarlyView.
This study examines how mesoscale convective systems (MCSs) over the Philippines are most frequent during boreal summer, while those in winter are longer‐lived and more intense due to cold surges and enhanced easterly moisture transport. Intraseasonal oscillations, such as the Madden‐Julian Oscillation (MJO) and the Boreal Summer Intraseasonal ...
Cathrene Lagare, Junshi Ito, Takeshi Yamazaki, Giuseppe Torri   +3 more
wiley   +1 more source