Results 151 to 160 of about 54,234 (265)

Using a social‐ecological macrosystems framework to understand how human activities alter ecological synchrony

open access: yesPeople and Nature, EarlyView.
Abstract Different aspects of ecological systems, biotic or abiotic, often fluctuate in coordinated patterns over space and time. Such high concordance between ecological processes is often referred to as ecological synchrony. Human activities, including and beyond climate change, have the potential to alter ecological synchrony by disrupting or ...
Yiluan Song   +9 more
wiley   +1 more source

Comfort in the canopy: How urban treescapes affect human thermal comfort in a temperate climate

open access: yesPeople and Nature, EarlyView.
Abstract People living in urban centres are exposed to higher levels of heat stress than those living outside of these areas; this is intensified by the urban heat island effect. Heat stress is a concern for the more vulnerable members of society and can exacerbate many medical conditions; excessive heat increases morbidity and mortality rates.
James Parker   +3 more
wiley   +1 more source

Functional validation of driver mutation‐specific uveal melanoma biomarkers: role of COL9A3 in cancer cell plasticity

open access: yesThe Journal of Pathology, EarlyView.
Abstract Uveal melanoma (UM) is a deadly ocular malignancy with well‐described genetic alterations that predict disease outcome. However, our current understanding of the biological underpinnings of high‐risk uveal melanoma progression remains relatively limited. Using RNA expression profiles from 250 patients with UM, we identified 12 novel biomarkers
QCC van den Bosch   +7 more
wiley   +1 more source

Development of a High‐Throughput Microarray Platform for Rapid, Low‐Cost Expanded Carrier Screening

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective To develop a customized expanded carrier screening (ECS) solution for 8271 variants of 265 genes. Based on a microarray platform, this solution demonstrates comparable accuracy to next‐generation sequencing (NGS) platform; however, it has a lower cost, a faster speed, and a simplified data—analysis process.
Jiazhen Chang   +11 more
wiley   +1 more source

Modeled Subsidence of Permafrost Terrain 2025–2050: North‐Central Alaska

open access: yesPermafrost and Periglacial Processes, EarlyView.
ABSTRACT A large fraction of the Alaska terrain is underlain by regolith that contains excess ice (ice that in volume exceeds the natural pore space). Possible loss of excess ice would lead to ground subsidence, which in turn would disturb and destabilize the ground surface.
Jaakko Putkonen   +8 more
wiley   +1 more source

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