Results 41 to 50 of about 128,938 (302)

Towards a more reliable historical reanalysis: Improvements for version 3 of the Twentieth Century Reanalysis system [PDF]

open access: yes, 2019
Historical reanalyses that span more than a century are needed for a wide range of studies, from understanding large‐scale climate trends to diagnosing the impacts of individual historical extreme weather events.
Smith, Catherine A.   +157 more
core   +2 more sources

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

reanalysis air temperature in Portugal [PDF]

open access: yes, 2023
Publisher Copyright: © 2023 Royal Meteorological Society.This study evaluates the reliability of ERA5 and ERA5-Land reanalysis datasets in describing the mean daily air temperature of four climate domains in mainland Portugal.
Almeida, Manuel   +3 more
core   +1 more source

Descriptors to Dynamics: A Materials and Device Perspective on in‐Materio Physical Reservoir Computing for Neuromorphic Edge Intelligence

open access: yesAdvanced Materials, EarlyView.
Intrinsic material dynamics are harnessed as computational resources for neuromorphic in‐materio physical reservoir computing. Defects, ionic motion, interfaces, percolation, geometry, and biasing shape transient states that provide fading memory, nonlinearity, and high‐dimensional projection for simple readout. A descriptor‐to‐dynamics framework links
Kshitij RB Singh   +5 more
wiley   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

open access: yesAdvanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo   +14 more
wiley   +1 more source

Phonological markedness effects in reanalysis [PDF]

open access: yes, 2023
Paradigms with conflicting data patterns can be difficult to learn, resulting in acquisition error. In this dissertation, I look at how paradigms are reanalyzed over time to gain insight into the factors that influence morphophonological learning ...
Kuo, Jennifer
core   +1 more source

Water Resource Reanalysis v1: Data Access and Model Verification Results

open access: yes, 2016
<p>Analysis of WWR1 produced by the eartH2Observe project.
Calton, Ben (5283880)   +5 more
core   +1 more source

Reanalysis of the Hamburg Storm Surge of 1962 [PDF]

open access: yes, 2013
In February 1962, Hamburg experienced its most catastrophic storm surge event of the 20th century. This paper analyses the event using the Twentieth Century Reanalysis (20CR) dataset.
Schwander, Mikhaël   +2 more
core   +2 more sources

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li   +15 more
wiley   +1 more source

An Evaluation of a 1/18o Resolution Regional Ocean Circulation Model of CROCO in the Southern Sunda Shelf

open access: yesIlmu Kelautan, 2023
The Coastal and Regional Ocean Community Model (CROCO) was applied to simulate the three dimensional ocean circulation on the southern Sunda Shelf with a horizontal resolution of 1/18o and 40 vertical layers.
Apriansyah Apriansyah   +4 more
doaj   +1 more source

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