Results 21 to 30 of about 51,523 (265)

Forcing the SAFY Dynamic Crop Growth Model with Sentinel-2 LAI Estimates and Weather Inputs from AgERA5 Reanalysis and CM SAF SARAH-3 Radiation Data for Estimating Crop Water Requirements and Yield

Remote Sensing
The continuous development of both numerical weather model outputs and remote sensing-derived products has enabled a wide range of applications across various fields, such as agricultural water management, where the need for robust gridded weather data ...
Anna Pelosi, Angeloluigi Aprile, Oscar Rosario Belfiore, Giovanni Battista Chirico   +3 more
doaj   +1 more source

Spatial Modeling of Precipitation Based on Data-Driven Warping of Gaussian Processes

Entropy, 2022
Modeling and forecasting spatiotemporal patterns of precipitation is crucial for managing water resources and mitigating water-related hazards. Globally valid spatiotemporal models of precipitation are not available.
Vasiliki D. Agou, Andrew Pavlides, Dionissios T. Hristopulos   +2 more
doaj   +1 more source

An Open-Access Web-Based Tool to Access Global, Hourly Wind and Solar PV Generation Time-Series Derived from the MERRA Reanalysis Dataset

Energies, 2017
Wind and solar energy resources are an increasingly large fraction of generation in global electricity systems. However, the variability of these resources necessitates new datasets and tools for understanding their economics and integration in ...
Madeleine McPherson, Theofilos Sotiropoulos-Michalakakos, LD Danny Harvey, Bryan Karney   +3 more
doaj   +1 more source

A Novel Multi-Input Multi-Output Recurrent Neural Network Based on Multimodal Fusion and Spatiotemporal Prediction for 0–4 Hour Precipitation Nowcasting

Atmosphere, 2021
Multi-source meteorological data can reflect the development process of single meteorological elements from different angles. Making full use of multi-source meteorological data is an effective method to improve the performance of weather nowcasting. For
Fuhan Zhang, Xiaodong Wang, Jiping Guan
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Comparison of Weighted Mean Temperature in Greenland Calculated by Four Reanalysis Data

Remote Sensing, 2022
The weighted mean temperature ( Tm) is a critical parameter for precipitable water vapor (PWV) retrieval in global navigation satellite system (GNSS) meteorology.
Chengcheng Luo, Feng Xiao, Li Gong, Jintao Lei, Wenhao Li, Shengkai Zhang   +5 more
doaj   +1 more source

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

Advanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li, Hao Tang, Qin Yu, Yuyang Zhang, Binglu Shi, Ying Kong, Leiyu Xu, Jingjing Shao, Chenghong Hu, Lingyu She, Zhe Wang, Haiyi Chen, Aleksandr V. Samorodov, Gang Cao, Xia Zhao, Yi Wang   +15 more
wiley   +1 more source

Radiation‐Induced Tumor‐Intrinsic LTβR N‐Glycosylation Suppresses Pyroptosis Through TRIM28‐Mediated PCBP2 SUMOylation to Promote Gastric Cancer Radioresistance

Advanced Science, EarlyView.
Radiotherapy triggers LTβR N‐glycosylation, enhancing its overall protein stability and nuclear retention. This accumulation drives TRIM28‐mediated PCBP2 SUMOylation, suppressing pyroptosis and conferring gastric cancer radioresistance. Therapeutically, a targeted nanoplatform (cRGD‐Lipo@EMD) effectively disrupts this regulatory axis, offering a highly
Weijie Zang, Yunlong Ji, Chunwang Zhou, Xiwen Li, Zhuang Lu, Guangze Zhang, Yu Chen, Wanjiang Xue, Yilin Hu   +8 more
wiley   +1 more source