Results 161 to 170 of about 3,262,397 (309)

Reasons for Reasons

Abstract This chapter describes the role of reasons for concept use, showing how they allow us to answer the authority question without crowding out other kinds of reasons that transcend preoccupation with human concerns or with the instrumentality of concepts.
openaire   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Competition Policy with Optimally Differentiated Rules Instead of "Per se Rules vs. Rule of Reason" [PDF]

: Both in US antitrust and EU competition policy a development to a broader appli-cation of rule of reason instead of per se rules can be observed. In the European discussion the attempt to base competition policy on a "more economic approach" is mainly ...
Arndt Christiansen and Wolfgang Kerber, Wolfgang Kerber   +1 more
core  

Emergency Department Visits for Suspected Suicide Attempts - United States, 2021-2025. [PDF]

MMWR Morb Mortal Wkly Rep
Singichetti B, Cammack AL, Rekieta P, Schumacher A, van Santen KL, Kaczkowski W, Radhakrishnan L, Anderson KN, Ballesteros MF, Lee R.   +9 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Exploring the prevalence of reasons adolescents feel unwelcome at school. [PDF]

PLoS One
Lucibello KM, Zheng L, Leatherdale ST, Patte KA.   +3 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Treatment terminations during radiation therapy: A retrospective descriptive single-center analysis. [PDF]

PLoS One
Ozen A, Harmankaya I, Ozdemır C, Halıcı M, Coskun O, Guler EB, Atılla O, Can S.   +7 more
europepmc   +1 more source

The reason to reason

, 2018
Uppsatsen baseras på designexperiment av undervisning med syftet att uppmuntra till kreativa resonemang. Studien genomfördes som ett antal undervisningstillfällen då närvarande elever presenterades för ett problem eller en frågeställning som inte var formulerad eller kunde lösas på samma sätt som typuppgifterna i läroboken.
openaire   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source