Results 221 to 230 of about 9,923,749 (308)

The association between violence exposure and general and cause-specific mortality in people using mental health services: cohort study. [PDF]

BJPsych Open
Rafi N, Stewart R, Jewell A, Shetty H, Bhavsar V.   +4 more
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Factors associated with late bedtimes, early wake-up times, and short sleep in adolescents on school nights. [PDF]

Sleep Adv
Charoenthammanon RS, Gooley JJ.
europepmc   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Biological Principles Successfully Guide Students' Generative Mechanistic Reasoning. [PDF]

CBE Life Sci Educ
Doherty JH, Todd KA, Wenderoth MP, VanDerSlik AL, Cole EJ.   +4 more
europepmc   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Prevalence of self-harm across urgent and emergency care settings among young people and factors associated with reattendance: protocol for a prospective cohort study. [PDF]

BMJ Open
Romeu D, Relton S, Burton C, Crum A, Chambers EV, Cottrell D, Guthrie E.   +6 more
europepmc   +1 more source

Increased Opioid Exposure in Older Adults During COVID-19: An Interrupted Times Series Analysis. [PDF]

Health Sci Rep
Abraham AJ, Steuart SR, Harris SJ, Bethel V.   +3 more
europepmc   +1 more source