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13.4 Example of a Reasonable Accommodation Policy
, 2023 This example is one way to approach a reasonable accommodation policy. It provides the rationale, identifies the responsible parties, connects it to associated processes and procedures, and highlights the important documents involved in policy ...
McNamee, Bridget A. +4 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Basic Income and the Rights of Persons with Disabilities
Age of Human Rights Journal, 2019 The Convention on the Rights of Persons with Disabilities presents a social approach to disabilities. In accordance with this conception, the origin of the discrimination suffered by persons with disabilities is mainly social because we have designed ...
José Luis Rey Pérez
doaj +3 more sources
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Interpreting "reasonable accommodation" of persons with disabilities in the South African workplace [PDF]
, 2022 LLM (Labour Law), North-West University, Potchefstroom CampusThis study aims to establish how reasonable accommodation requirements for the fair and equal treatment of persons with disabilities should be interpreted and applied in South African labour ...
Roberts, Carel Pieter
core
Distinguishing "Reasonable Accommodation" From Physical Assistance in Aid-in-Dying. [PDF]
Am J Bioeth, 2023 Astrachan I, Berkman BE.
europepmc +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Reasonable Accommodation and Disability: a Comparative Analysis [PDF]
After a brief overview of the content of the United Nations Convention on the Rights of Persons with Disabilities, the present paper provides a comparative analysis of European Union law, the Italian, Spanish, Indian and US legal systems on the subject ...
Zampieri, Giovanna +3 more
core +1 more source