Results 91 to 100 of about 16,476,009 (293)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The Reason, the Understanding, and Time. [PDF]

open access: yesPhilosophy and Phenomenological Research, 1961
Daniel S. Robinson, Arthur O. Lovejoy
  +4 more sources

Criminal procedure finishing within a reasonable time

open access: yes, 2014
Autore bakalaura darbā analizē dažādus aspektus, kas saistīti ar kriminālprocesa pabeigšanu saprātīgā termiņā, piemēram, tiesību sākuma un beigu posmu, pēta, kādi aspekti ietekmē, vai kriminālprocess ir pabeigts saprātīgā termiņā, kā arī sekas saprātīga ...
Riekstiņa, Renāte
core  

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

On constitutional and conventional doubts with the Consumer Bankruptcy Actdoes the several year plan to pay off debts in the Consumer Bankruptcy Act represent a violation of the right to trial within a reasonable time? [PDF]

open access: yesZbornik Radova Pravnog Fakulteta u Splitu, 2016
The precedential character of the European Convention law for the protection of human rights and fundamental freedoms (further in the text referred to as: European Convention or ECHR), which through the practice of the European Court of Human Rights ...
Sanja Grbić, Dejan Bodul
doaj  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

The rule of law and reasonable suspicion

open access: yes, 2011
New South Wales and Victorian Parliaments have introduced legislation that allows extended police powers in designated areas. In these areas, police can conduct non-invasive searches of individuals without the need for a warrant and without the need for
Gray, Anthony
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Asigurarea termenului rezonabil în procesul civil: standarde convenționale și riscuri [PDF]

open access: yesRevista Institutului Naţional de Justiţie, 2015
Within a fair trial, a major role is occupied by respecting the right to trial within a reasonable time, especially aft er the decision of the European Court of Human Rights in the case Kudla against Poland in 2000.
Sanduţa Victoria
doaj  

Reasonable Doubt in Islamic Law [PDF]

open access: yes, 2015
Doubt pervades most laws, becomes alarming when it arises in criminal law, and seems especially discomfiting in the context of Islamic criminal law. In the high-stakes area of American criminal prosecutions, dubious facts or ambiguous laws can result in ...
Rabb, Intisar A., Rabb, Intisar
core  

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