Results 101 to 110 of about 16,476,009 (293)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
REASONABLE TIME FOR CRIMINAL PROCEEDINGS
, 2019 В данной статье автор анализирует принцип уголовного судопроизводства, как разумный срок, устанавливает отсутствие полной регламентации в отношении применения данного принципа, на стадиях уголовного процесса, выясняет проблемы определения и прикладного ...
Пирожкова Екатерина Сергеевна
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Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Pravo, 2016 THE topic of this work is a professional-critical analysis of fifteen-year reforms of criminal procedural legislation of Republic of Serbia in terms of normative solutions contributing to the practical realization of the right to trial within a ...
Srđan Cvijanović
doaj
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Reasonable time in criminal proceedings as a human rights
, 2018 Maģistra darbā ar nosaukumu „Saprātīgs termiņš kriminālprocesā kā cilvēktiesību princips” tiks analizēta saprātīga termiņa nozīme un izpratne kriminālprocesā.
Asatrjana, Jerana
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Completion of criminal proceeding within a reasonable time
, 2020 Bakalaura darba temats ir “Tiesības uz kriminālprocesa pabeigšanu saprātīgā termiņā”. Darba mērķis ir izpētīt saprātīga termiņa vēsturisko izcelšanos, nozīmi, saturu, arī tos kritērijus, kas ietekmē kriminālprocesa pabeigšanu saprātīgā termiņā, kā arī ...
Rudzīte, Līga
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Completion of criminal process within a reasonable time, evaluation of reasonable time limits
, 2016 Kriminālprocesa pabeigšana saprātīgā termiņā joprojām ir aktuāla problēma un kamēr šī problēma pastāv kriminālprocesa ietvaros Latvijā, nevar runāt par kriminālprocesa taisnīgu veikšanu un no konstitūcijas izrietošu vērtību ievērošanu.
Riks, Mārcis
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