Results 91 to 100 of about 23,193 (292)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Rationality and Reasonableness in Legal Theory
Problema: Anuario de Filosofía y Teoría del Derecho, 2014 En este trabajo se examina el ensayo de Guillermo Lariguet intitulado “Analytical Legal Philosophy Reloaded”, y se ofrecen dos interpretaciones de su proyecto de “renovar” la filosofía analítica del derecho.
Carlos Montemayor
doaj +1 more source
Reasons as Premises of Good Reasoning [PDF]
Pacific Philosophical Quarterly, 2015 AbstractMany philosophers have been attracted to the view that reasons are premises of good reasoning – that reasons to φ are premises of good reasoning towards φ‐ing. However, while thisreasoning viewis indeed attractive, it faces a problem accommodating outweighed reasons.
openaire +3 more sources
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
The Institute of Corporate Traditions in the Management of a Russian Company
Современная конкуренцияThe article is devoted to the study of the institution of “corporate traditions” - a set of rules that is increasingly actively used by arbitration courts, which are not explicitly provided for by Russian legislation, but appeal to the actually formed ...
Oleg V. Osipenko
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
BMC Health Services Research, 2005 Background Priority setting, also known as rationing or resource allocation, occurs at all levels of every health care system. Daniels and Sabin have proposed a framework for priority setting in health care institutions called 'accountability for ...
Martin Douglas K +3 more
doaj +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
The real problem with Rawlsian reasonableness
, 2021 Rawlsian “reasonableness” has been criticized as “loaded” (Stout 2004: 184), “chimerical” (Young 2005: 308) or “entirely circular” (Mulhall and Swift 2003: 483). Yet these reactions often equivocate on the meaning of reasonableness (Freeman 2004: 2063-5).
BURKS, Deven
core +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source