Results 121 to 130 of about 9,000,818 (348)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Unemployment Through Layoffs: What Are the Underlying Reasons? [PDF]

open access: yes, 2005
CRS_April_2005_Unemployment_Through_Layoffs.pdf: 6598 downloads, before Oct.
Levine, Linda
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

POS0644 UNDERSTANDING REASONS INFLUENCING PATIENTS’ PREFERENCES FOR THE MODE OF ADMINISTRATION OF ANTI-RHEUMATIC DRUGS IN INFLAMMATORY ARTHRITIS. A QUALITATIVE STUDY [PDF]

open access: gold, 2023
Catherine Beauvais   +6 more
openalex   +1 more source

Moral Hedging and Responding to Reasons [PDF]

open access: yes, 2019
In this paper, I argue that the fetishism objection to moral hedging fails. The objection rests on a reasons-responsiveness account of moral worth, according to which an action has moral worth only if the agent is responsive to moral reasons. However, by
Hicks, Amelia
core  

Proprietary Reasons and Joint Action [PDF]

open access: yes
Some of the reasons one acts on in joint action are shared with fellow participants. But others are proprietary: reasons of one’s own that have no direct practical significance for other participants.
A Roth   +16 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Recent Work on Internal and External Reasons [PDF]

open access: yes, 2017
This paper examines some recent arguments for internalism that (i) appeal to an analogy between practical and theoretical reasons, (ii) look toward our practices of reasoning with others, or (iii) tie reasons to good deliberation.
Brunero, John
core  

Do We Have Reasons to Obey the Law? [PDF]

open access: yes, 2020
Instead of the question, ‘do we have an obligation to obey the law?,’ we should first ask the more modest question, ‘do we have reasons to obey the law?’ This paper offers a new account of the notion of the content-independence of legal reasons in terms ...
Flanigan, Edmund Tweedy
core  

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