Results 221 to 230 of about 9,000,818 (348)

Reasons for Android OS Popularity [PDF]

, 2014
Morozova, T.I., Saveliev, V. A., Stanislavskiy, Denis   +2 more
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Do general practitioners and community pharmacists want information on the reasons for drug therapy changes implemented by secondary care?

, 1997
Angela Munday, B E Kelly, J. W. E. Forrester, Angela Timoney, E. M. McGovern   +4 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Reasons for not using e-cigarettes among adults who smoke: findings from the 2019-2021 Euromonitor International's Voice of the Consumer: Nicotine Survey in 20 countries. [PDF]

BMC Public Health
Pei D, Sharapova S, Popova L.
europepmc   +1 more source

The Space of Reasons and the Community of Communication of Reasoners

, 2020
Matthias Kettner, Laura Molina Molina
openalex   +1 more source

Increasing numbers of nonaneurysmal subarachnoid hemorrhage in the last 15 years: antithrombotic medication as reason and prognostic factor? [PDF]

, 2015
Juergen Konczalla, Sepide Kashefiolasl, Nina Brawanski, Christian Senft, Volker Seifert, Johannes Platz   +5 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Forgoing Healthcare and Insurance Premiums Trends: A 15-Year Population-Based Study in Geneva, Switzerland. [PDF]

Int J Public Health
Nehme M, Dumont R, Heritier H, Lamour J, Mechoullam S, De Ridder D, Guessous I.   +6 more
europepmc   +1 more source

Prevalence, reasons, and perceived effects of Khat chewing among students of a college in Gondar town, Northwestern Ethiopia: A cross-sectional study

, 2015
FS Teni, A S Surur, Aster Hailemariam, Amba Josiane Aye, Getinet Adugna Mitiku, A E Gurmu, Belay Tessema   +6 more
openalex   +1 more source