Results 241 to 250 of about 8,946,291 (316)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Barriers and Opportunities to Include Underrepresented Population Groups in Vaccine Trials: Cross-Sectional, Observational, Online Survey Study From the VACCELERATE Research Network.

JMIR Public Health Surveill
Tanriover MD, Poulimeneas D, Tsopela GC, Kopsidas I, Argyropoulos C, Di Marzo R, Valdenmaiier O, Jakobsen SF, Valle Simon P, Carcas-Sansuan AJ, Olesen OF, Cornely OA, Pana ZD, Zaoutis T, Akova M.   +14 more
europepmc   +1 more source

Self-reported handwashing frequency among pet and non-pet owners in the German adult population in 2023: a post-pandemic replication study. [PDF]

BMC Public Health
Nettelrodt KME, von Lengerke T.
europepmc   +1 more source

Harry G. Frankfurt, The Reasons of Love [PDF]

, 2004
Kawall, Jason
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Gun ownership for political protection or armed political expression: a nationally representative analysis of differences in 2025 vs. 2023. [PDF]

Inj Epidemiol
Ward JA, Valek RA, Jones VC, Mason L, Crifasi CK.   +4 more
europepmc   +1 more source

Characteristics, Prognosis and Reasons for Opting-Out of Treatment in Patients with Untreated Pancreatic Cancer. [PDF]

Curr Oncol
Ladekarl M, Stender MT.
europepmc   +1 more source

Pediatric dental treatment under general anesthesia: a retrospective analysis of clinical indications and a survey of pediatric dentist referral practices. [PDF]

Front Dent Med
Fux-Noy A, Raz M, Masrawa K, Shmueli A, Halperson E, Moskovitz M.   +5 more
europepmc   +1 more source

Lost to follow-up while undergoing intravitreal injection therapy: barriers to adherence in a real-world setting. [PDF]

Int J Retina Vitreous
Licht A, Mavris Y, Latz C, Schuster AK, Ponto KA, Mirshahi A.   +5 more
europepmc   +1 more source

A Retrospective Audit of Healthcare-Associated Infections in Patients Who Are Optimised for Discharge at a Tertiary Medical Centre. [PDF]

Cureus
Barrett C, Shankar Kumar H, Singleton H.
europepmc   +1 more source