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Journal of Virology, 2018 Exchange of gene segments through reassortment is a major feature of influenza A virus evolution and frequently contributes to the emergence of novel epidemic, pandemic, and zoonotic strains.
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Influenza A Virus Reassortment
2014Reassortment is the process by which influenza viruses swap gene segments. This genetic exchange is possible due to the segmented nature of the viral genome and occurs when two differing influenza viruses co-infect a cell. The viral diversity generated through reassortment is vast and plays an important role in the evolution of influenza viruses ...
John, Steel, Anice C, Lowen
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Is rotavirus a population of reassortants?
Trends in Microbiology, 1995Rotaviruses appear to exist as heterogeneous populations of reassortants and related variants. This phenomenon is consistent with the quasispecies concept of RNA viruses, and suggests that gene reassortment is a crucial evolutionary mechanism for this segmented virus.
V, Gouvea, M, Brantly
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WC3 reassortant vaccines in children
1996Bovine rotavirus strain WC3 (P7[5], G6) administered at the 12th passage level was well tolerated clinically in infants and efficiently induced serum virus neutralizing antibody (VNA) with bovine rotavirus G6 specificity. The protective efficacy of WC3 vaccine against all rotavirus disease was inconsistent, varying in four separate trials from 76% to 0%
H F, Clark +7 more
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Reassortment among picobirnaviruses found in wolves
Archives of Virology, 2016We conducted a viral metagenomics study in diarrheic free-ranging wolves in Portugal, revealing for the first time the presence of reassortant picobirnaviruses. These viruses shared identical capsid segments together with diverse RNA-dependent RNA polymerase segments.
Conceição-Neto, Nádia +10 more
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Generation of reassortants between African arenaviruses
Virology, 1992Lassa (LAS) and Mopeia (MOP) viruses are African arenaviruses which are carried by wild rodents and occasionally transferred to humans. In humans and nonhuman primates, Lassa causes mortality in 60% of untreated cases, whereas Mopeia does not cause mortality and has been known to protect monkeys from lethal challenge with Lassa.
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Joint Inference of Migration and Reassortment Patterns for Viruses with Segmented Genomes
Molecular Biology and Evolution, 2022Timothy G Vaughan +2 more
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