Results 41 to 50 of about 34,063 (269)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Yük Taşımacılığından Devlete İsyana: Ermeni Hamallar
Vakanüvis Uluslararası Tarih Araştırmaları Dergisi, 2018 Yük taşıyan insanlar bir devletin sosyal ve siyasi hayatında ne kadar etkili olabilirler? Anadolu’nun farklı kentlerinde ve bilhassa başkent İstanbul’da, daha çok iskele ve limanlarda çalışan Ermeni hamallar incelendiğinde bu soruya çok ilginç cevaplar ...
Abdullah LÜLECİ
doaj
Local resistance against the Derg in Ethiopia: The case of Admasu Belay rebellion
Cogent Social Sciences, 2022 As it is known war and rebellion are very common in Ethiopia due to internal and external factors. Since the ancient times governments and leaders in the country faced a variety of rebellions.
Solomon Ashagrie
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Fokus, 2017 This article begins with the writer's "disquiet" about the massively absorbed word amuk in English (Europe in general). Whereas the original amuk is a word in Javanese Kawi, which can also be found in Malay, Indonesian, and Tagalok.
Aris Fauzan
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Estudios AtacameñosEste artículo consta de una introducción y de la transcripción del expediente de la rebelión acontecida en Ingaguasi en 1775 (jurisdicción de la provincia de Atacama).
Nelson Castro F +2 more
doaj +1 more source
Yahyâ b. Zeyd İsyanı ve Horasan’daki Etkileri
Cumhuriyet İlahiyat Dergisi, 2020 Emevîler dönemi önemli iç gelişmelerden biri Ehl-i beyt mensupları tarafından gerçekleştirilen isyanlardır. Kerbelâ’dan sonra 122/740 yılında Zeyd b. Ali tarafından Kûfe’de gerçekleştirilen isyan başarısızlıkla sonuçlanmıştır.
Cahid Kara
doaj +1 more source