Results 71 to 80 of about 304,891 (277)

Rebellion In Mata Hari The Spy Novel (2016) By Paulho Coelho: A Feminist Analysis [PDF]

open access: yes, 2018
This research describe about a person named Margaret Zelle who acts as a spy for the German state and has the secret name of H21 and has a stage name that is Mata Hari. This research describes how Paulo Coelho described the rebellion in the novel The Spy.
-, Dr. Phil Dewi Candraningrum   +1 more
core  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

THE BARBAROUS MASSACRE RECONSIDERED: THE POWHATAN UPRISING OF 1622 AND THE HISTORIANS [PDF]

open access: yes, 1978
The Powhatan Uprising of March 22, 1621/22, was the single most significant event of Anglo-Indian relations in Virginia. An early example of a native culture’s rebellion against intruding European civilization, the uprising climaxed a mere decade and a ...
Fausz, J. Frederick
core   +1 more source

Introduction. Out of Hidden India: Adivasi Histories, Stories, Visual Arts and Performances [PDF]

open access: yes, 2015
This issue of Anglistica AION is dedicated to indigenous India and to some of its forms of emerging subjectivity. After having been studied by ethnoanthropologists as cultural exceptions or worse after having embodied the stereotype of the ‘born ...
Ciocca, Rossella, DAS GUPTA, Sanjukta
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The Desperate Rebels of Shimabara: The Economic and Political Persecutions And the Tradition of Peasant Revolt

open access: yes, 2016
The Shimabara Rebellion has been studied throughout history by historians of East Asia. Originally conceived by both Japanese and Western scholars as a religious revolt against the anti-Christian Tokugawa government, later scholars contended that the ...
Farias, Jake A
core  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

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