Results 71 to 80 of about 307,248 (265)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Εξεγέρσεις στη Νότια Ροδεσία 1896-1897

open access: yesMos Historicus
The present study examines the rebellion of Ndebele and Shona against the rule of the British South Africa Company in 1896-97. The purpose of this study is to point out the nature, the causes, the development, and the results of the natives’ anti ...
Antonios Chiotellis
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Rocky Horror: A Study in Shadows and Flight [PDF]

open access: yes, 2018
“Rocky Horror: A Study in Shadows and Flight” is a creative nonfiction piece that analyzes the infamous legacy left by the cult classic, The Rocky Horror Picture Show.
Chin, Julia M.
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Rebellion, repression and welfare [PDF]

open access: yes
I develop a dynamic model of social conflict whereby manifest grievances of the poor generate the incentive of taking over political power violently. Rebellion can be an equilibrium outcome depending on the level of preexisting inequality between the ...
Juan F. Vargas
core  

Rebellion In Mata Hari The Spy Novel (2016) By Paulho Coelho: A Feminist Analysis [PDF]

open access: yes, 2018
This research describe about a person named Margaret Zelle who acts as a spy for the German state and has the secret name of H21 and has a stage name that is Mata Hari. This research describes how Paulo Coelho described the rebellion in the novel The Spy.
-, Dr. Phil Dewi Candraningrum   +1 more
core  

Book review: Spirit of rebellion. Labor and religion in the new cotton south [PDF]

open access: yes, 2012
International audienceThis article provides formal definitions characterizing well-formed composition of components in order to guarantee their safe deployment and execution.
Henrio, Ludovic   +3 more
core   +5 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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