Results 71 to 80 of about 8,181,745 (306)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Improving the mechanical characteristics of environmentally friendly concrete using fly ash and brick powder as partial sand replacements [PDF]

open access: yesGrađevinski Materijali i Konstrukcije
Infrastructure and urbanization drive the demand for concrete, which puts pressure on natural resources and jeopardizes the ecosystem. Incorporating recycled materials into concrete can fulfill this demand without sacrificing quality. This study examines
Filali Saloua   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Recovery of the 20 Hz Rebound to Tactile and Proprioceptive Stimulation after Stroke

open access: yesNeural Plasticity, 2018
Sensorimotor integration is closely linked to changes in motor-cortical excitability, observable in the modulation of the 20 Hz rhythm. After somatosensory stimulation, the rhythm transiently increases as a rebound that reflects motor-cortex inhibition ...
Eeva Parkkonen   +3 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Exploiting Integrated Demand Response for Operating Reserve Provision Considering Rebound Effects

open access: yesIEEE Access, 2022
Electricity-driven thermostatically controlled loads (TCLs), e.g., air conditioners (ACs), have been widely utilized in demand response (DR) to provide operating reserve for power systems.
Xiaoming Zhou   +6 more
doaj   +1 more source

Adiposity rebound and cardiometabolic health in childhood: results from the Generation XXI birth cohort.

open access: yesInternational Journal of Epidemiology, 2021
BACKGROUND We aimed to evaluate the association of adiposity rebound (AR) timing on cardiometabolic health in childhood. METHODS Participants were part of the Generation XXI birth cohort, enrolled in 2005/2006 in Porto.
M. J. Fonseca, Carla Moreira, A. Santos
semanticscholar   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Contribution of Plantar Fascia and Intrinsic Foot Muscles in a Single-Leg Drop Landing and Repetitive Rebound Jumps: An Ultrasound-Based Study

open access: yesInternational Journal of Environmental Research and Public Health, 2021
The plantar fascia and intrinsic foot muscles (IFM) modulate foot stiffness. However, it is unclear whether the corresponding ultrasonography findings reflect it.
M. Morikawa   +8 more
semanticscholar   +1 more source

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