Results 61 to 70 of about 103,970 (298)
Block Motion Changes in Japan Triggered by the 2011 Great Tohoku Earthquake [PDF]
, 2017 Plate motions are governed by equilibrium between basal and edge forces. Great earthquakes may induce differential static stress changes across tectonic plates, enabling a new equilibrium state.
Loveless, John P., Meade, Brendan J.
core +3 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
An Infrared Thermography Approach to Evaluate the Strength of a Rock Cliff
Remote Sensing, 2021 The mechanical strength is a fundamental characteristic of rock masses that can be empirically related to a number of properties and to the likelihood of instability phenomena.
Marco Loche +9 more
doaj +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Mechanical properties of Lop Nor salt rock fillers for subgrade and its forecast model construction
Frontiers in Materials, 2023 A deep exploration was conducted on the evolution law of the mechanical properties of salt rock fillers under the influence of different forming parameters in the Lop Nor area to promote the engineering application process of salt rock.
Cheng Cheng +6 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Pregabalin abuse and dependence during insomnia and protocol for short-term withdrawal management with diazepam: examples from case reports [PDF]
Sleep ScienceIntroduction:: Pregabalin (PGN) is an anxiolytic, analgesic, antiepileptic, and hypnotic medication. There are concerns about its abuse in the community for managing chronic insomnia and other risks when assumed in overdose or combination with other ...
Basavaraja Papanna +4 more
doaj +1 more source
Annular billiard dynamics in a circularly polarized strong laser field [PDF]
, 2011 We analyze the dynamics of a valence electron of the buckminsterfullerene molecule (C60) subjected to a circularly polarized laser field by modeling it with the motion of a classical particle in an annular billiard.
Chandre, Cristel +3 more
core +6 more sources
, 2019 Purpose: This investigation examined the inter-day reliability and usefulness of reactive strength index (RSI) derived from a maximal 5 rebound jump test (5max RJT) and a maximal 10 rebound jump test (10/5 RJT). Methods: Twenty male field sport athletes (24.5±3.0 y; 1.78±0.1 m; 84.9±5.2 kg) performed 2 maximal repetitions of the 5max RJT and the 10/5 ...
Comyns, Thomas M. +4 more
openaire +2 more sources