Results 71 to 80 of about 105,063 (289)

Effect of Trampoline rebound exercises on cardiovascular indices, body mass index, and lipid profile of obese and overweight women

Yafteh Lorestan University of Medical Sciences, 2022
Background: Trampoline rebound is one of the recent interesting exercises. The present study aimed to investigate the effect of six weeks of trampoline rebound exercises on cardiovascular indices, body mass index, and lipid profile of obese and overweight women.
openaire   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Energy substitution, technical change and rebound effects [PDF]

, 2014
This paper investigates the relationships between energy efficiency improvements by producers, the ease of substitution between energy and other inputs and the size of the resulting “rebound effects”.
Allan, Apostolakis, Azar, Berndt, Berndt, Berndt, Berndt, Bhattacharyya, Binswanger, Blackorby, Bosetti, Broadstock, Burniaux, Christensen, Conrad, Edenhofer, Frondel, Frondel, Frondel, Frondel, Gerlagh, Glomsrod, Goulder, Grepperud, Hanley, Hertel, Hicks, Hogan, Hogan, Kemfert, Kemfert, Kermfert, Koetse, Lecca, Löschel, Manne, Manne, Manne, Manne, McFadden, Patterson, Popp, Raj, Sanstad, Sato, Sato, Saunders, Saunders, Saunders, Saunders, Saunders, Saunders, Sorrell, Stern, Steve Sorrell, Sue Wing, Sue Wing, Sue Wing, Turner, Van der Werf, Van der Zwaan   +60 more
core   +2 more sources

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Semi-analytical homologous solutions of the gravo-magnetic contraction

, 2003
We propose an extension of the semi-analytical solutions derived by Lin et al. (1965) describing the two-dimensional homologous collapse of a self-gravitating rotating cloud having uniform density and spheroidal shape, which includes magnetic field (with
Hennebelle, P.
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Pregabalin abuse and dependence during insomnia and protocol for short-term withdrawal management with diazepam: examples from case reports [PDF]

Sleep Science
Introduction:: Pregabalin (PGN) is an anxiolytic, analgesic, antiepileptic, and hypnotic medication. There are concerns about its abuse in the community for managing chronic insomnia and other risks when assumed in overdose or combination with other ...
Basavaraja Papanna, Carlo Lazzari, Kapil Kulkarni, Sivasankar Perumal, Abdul Nusair   +4 more
doaj   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source