Results 61 to 70 of about 105,063 (289)

Wetting-drying-freezing-thawing cycle effect on the hydro-mechanical behaviour of Yanji swelling mudstone

open access: yesJournal of Rock Mechanics and Geotechnical Engineering, 2023
Swelling geomaterials in northwestern and northeastern China are exposed to both seasonal wetting-drying (DW) and freezing-thawing (FT) processes. The influence of full-process wetting-drying-freezing-thawing (WDFT) cycles on their hydro-mechanical ...
Zhixiong Zeng, Lingwei Kong
doaj   +1 more source

Attachment styles and personal growth following romantic breakups: The mediating roles of distress, rumination, and tendency to rebound [PDF]

open access: yes, 2013
© 2013 Marshall et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
B Kleim   +49 more
core   +3 more sources

Separating Algorithms From Questions and Causal Inference With Unmeasured Exposures: An Application to Birth Cohort Studies of Early Body Mass Index Rebound

open access: yesAmerican Journal of Epidemiology, 2021
Abstract Observational studies reporting on adjusted associations between childhood body mass index (BMI; weight (kg)/height (m)2) rebound and subsequent cardiometabolic outcomes have often not paid explicit attention to causal inference, including definition of a target causal effect and assumptions for unbiased estimation of that ...
Izzuddin M, Aris   +7 more
openaire   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

REM sleep deprivation during 5 hours leads to an immediate REM sleep rebound and to suppression of non-REM sleep intensity [PDF]

open access: yes, 1990
Nine healthy male subjects were deprived of REM sleep during the first 5 h after sleep onset. Afterwards recovery sleep was undisturbed. During the deprivation period the non-REM EEG power spectrum was reduced when compared to baseline for the ...
Achermann   +22 more
core   +4 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Recovery of the 20 Hz Rebound to Tactile and Proprioceptive Stimulation after Stroke

open access: yesNeural Plasticity, 2018
Sensorimotor integration is closely linked to changes in motor-cortical excitability, observable in the modulation of the 20 Hz rhythm. After somatosensory stimulation, the rhythm transiently increases as a rebound that reflects motor-cortex inhibition ...
Eeva Parkkonen   +3 more
doaj   +1 more source

Body Mass Index Changes and Insulin Resistance at Age 4: A Prospective Cohort Study

open access: yesFrontiers in Endocrinology, 2022
ObjectivesThe objective of this study is to investigate whether body mass index (BMI) changes are associated with fasting glucose and insulin resistance (IR) in early childhood.MethodsFrom the Environment and Development of Children (EDC) cohort, 334 ...
Hye Jin Lee   +6 more
doaj   +1 more source

Perturbation Analysis of a General Polytropic Homologously Collapsing Stellar Core

open access: yes, 2009
For dynamic background models of Goldreich & Weber and Lou & Cao, we examine 3-dimensional perturbation properties of oscillations and instabilities in a general polytropic homologously collapsing stellar core of a relativistic hot medium with a ...
Arnett   +90 more
core   +1 more source

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