Results 41 to 50 of about 53,348 (267)

Change in Mental Health and Resilience in Childhood Cancer Survivors After Attending a Person‐Centred State‐of‐the‐Art Late Effects Clinic—on Behalf of the PanCareFollowUp Consortium

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Person‐centred follow‐up care based on evidence‐based clinical practice guidelines and providing individualised information should help to inform and reassure survivors about their medical and psychosocial situation and provide treatment and support where needed.
Gisela Michel   +36 more
wiley   +1 more source

Factors associated with viral suppression and rebound among adult HIV patients on treatment: a retrospective study in Ghana

open access: yesAIDS Research and Therapy, 2022
Background Viral suppression remains the most desired outcome in the management of patients with Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS) and this can be achieved by an effective Antiretroviral Therapy (ART).
Stephen Opoku   +11 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Rapid Eye Movement (REM) rebound on initial exposure to CPAP therapy: a systematic review and meta-analysis

open access: yesSleep Science and Practice, 2017
Objective Rapid Eye Movement (REM) rebound is a polysomnographic phenomenon where a substantial increase in REM sleep is noted in patients with untreated obstructive sleep apnea (OSA) when first undergoing continuous positive airway pressure (CPAP ...
Gaurav Nigam   +2 more
doaj   +1 more source

Estimation of uniaxial compressive and indirect tensile strengths of intact rock from Schmidt hammer rebound number

open access: yesJournal of the Mechanical Behavior of Materials, 2023
A number of destructive and non-destructive tests were conducted on rock samples collected from various zones in northern Iraq. So far, for Iraqi rocks, few studies have correlated Schmidt hammer rebound (R) with both unconfined compressive strength (UCS)
Fadhil Amjad Ibrahim   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

A Novel Intelligent Rebound Hammer System Based on Internet of Things

open access: yesMicromachines, 2023
In order to improve the test efficiency of concrete strength and ensure measured data reliability, we present a novel intelligent rebound hammer system which is based on the Internet of Things (IoT) and speech recognition technology.
Zongqiang Pang   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Reliability of using nondestructive tests to estimate compressive strength of building stones and bricks

open access: yesAlexandria Engineering Journal, 2012
This study aims to investigate the relationships between Schmidt hardness rebound number (RN) and ultrasonic pulse velocity (UPV) versus compressive strength (fc) of stones and bricks.
Ali Abd Elhakam Aliabdo   +1 more
doaj   +1 more source

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