Results 221 to 230 of about 964,987 (290)
Robots and Minimal, Physics‐Informed Features: A Hybrid Framework for Enzyme Catalysis
Robotic experimentation and physics‐informed machine learning combine to predict enzyme substrate scope. With a handful of interpretable features derived from docking and quantum mechanics calculations, our model rivals descriptor‐heavy AI approaches and extrapolates to unseen substrates and enzyme classes.
Natalia Onishchenko +8 more
wiley +1 more source
Comparing the safety and quality of video versus telephone telehealth using simulated consultations on fictional medications for an Australian community sample: a randomised controlled trial protocol. [PDF]
Jiang Y +9 more
europepmc +1 more source
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu +5 more
wiley +1 more source
Are restudy decisions reactively altered by judgments of learning? Insights from related and unrelated word pairs. [PDF]
Ingendahl F, Undorf M.
europepmc +1 more source
Non‐canonical amino acids (ncAAs) enhance peptide therapeutics but remain difficult to model computationally. SinCAA, a similarity‐enhanced pretraining framework, jointly optimizes contrastive learning guided by a novel conformational similarity metric with masked node reconstruction, capturing both functional relationships and chemical identity of ...
Chencheng Xu +8 more
wiley +1 more source
Prioritizing meaning: value, prediction, and age differences in sentence processing. [PDF]
Chung YMW, Federmeier KD.
europepmc +1 more source
By merging centrifugal microfluidics, precise temperature control, and AI image recognition, T‐PhaseMap transforms biomolecular condensate phase mapping into a rapid, temperature‐resolved workflow. It generates 3D composition–temperature phase diagrams within 30 min, resolves four phase states, and uncovers temperature‐dependent heparin sodium ...
Jiashuo Li +6 more
wiley +1 more source
Decentralizing Clinical Tumor Exome Analysis: On-Premises GPU-Based Secondary Analysis in a Clinical Molecular Laboratory. [PDF]
Ahluwalia P +7 more
europepmc +1 more source

