Results 91 to 100 of about 5,492,622 (265)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Received signal strength gradient estimation for mobile networks

open access: yes, 2010
This paper considers the question: As a receiver moves along a trajectory, is its received signal strength (RSS) increasing or decreasing? This is an important question for mobile receivers to answer in order to maintain or improve connectivity within ...
Brian M. Sadler   +3 more
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Received signal strength based location estimation for emergency cases [PDF]

open access: yes, 2019
The success of the localization highly depends on the accuracy of the localization algorithm. One of the most well-known and simple localization technique is received signal strength indicator based location estimation which relies on the measuring the ...
Karataş, Onur, Ekti, Ali Rıza
core   +1 more source

Primary User Localization and Its Error Analysis in 5G Cognitive Radio Networks

open access: yesSensors, 2019
It is crucial to estimate the location of primary users (PUs) for the development of cognitive radio networks (CRNs). Great efforts have been made in the past to develop localization algorithms with better accuracy but low computation.
Nasir Saeed   +3 more
doaj   +1 more source

In-vehicle localization based on multi-channel Bluetooth Low Energy received signal strength indicator

open access: yesInternational Journal of Distributed Sensor Networks, 2020
High-precision in-vehicle localization is the basis for both in-vehicle location-based service and the analysis of the driver or passengers’ behaviors.
Gao Yuan   +4 more
doaj   +1 more source

Received-Signal-Strength-Based Logical PositioningResilient to Signal Fluctuation

open access: yes, 2008
Positioning based on received signal strengths from basestations is highly sensitive to the effects of signal attenuation, reflection, and scattering.
Thomas Locher Roger Wattenhofer Aaron
core  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy