Results 231 to 240 of about 809,381 (295)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Elevated non-invasive liver fibrosis scores at admission are independent risk factors for severe COVID-19: a retrospective cohort study from 2020 to 2024. [PDF]

Front Med (Lausanne)
Cabrejos Hirashima L, Naiman NE, Malik AA, Jain MK.   +3 more
europepmc   +1 more source

Receiver Functions in Seismology

, 2007
openaire   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Screening cognitive decline in older adults using umami hypogeusia and oral diadochokinesis: a cross-sectional study. [PDF]

BMC Geriatr
Fujiwara A, Mizutani S, Kawabata Y, Yamazoe J, Kashiwazaki H.   +4 more
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

High-performance 100 Gbps free-space optical communication via optical pin beam receiver. [PDF]

Commun Eng
Guan M, Liu Y, Wang H, Xiao H, Lu H, Zhang H, Jiang H, Sun C, Liang H, Xu C, Gao L, Mei H, Li Y, Wu J, Chen Z, Zhang Z.   +15 more
europepmc   +1 more source

Receiver Location Optimization for Heterogeneous S-Band Marine Transmitters in Passive Multistatic Radar Networks via NSGA-II. [PDF]

Sensors (Basel)
Li X, He P, Song J, Wang Z.
europepmc   +1 more source

Covert underwater communication through cepstrum modulation mimicking Pseudorca crassidens whistles using machine learning. [PDF]

Sci Rep
Bilal M, Zuberi HH, Jaffar A, Riaz W, Khan MA, Alharbi A, Miyajan A, Liu S.   +7 more
europepmc   +1 more source