Results 101 to 110 of about 651,813 (285)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Vulnerability to poverty: An empirical comparison of alternative measures [PDF]
The recent common feeling about a skyrocketing economic risk has drawn increasing attention to its role and consequences on individuals' welfare.
Celidoni, Martina
core +1 more source
AUK: a simple alternative to the AUC [PDF]
The area under Receiver Operating Characteristic (ROC) curve, also known as the AUC-index, is commonly used for ranking the performance of data mining models. The AUC has many merits, such as objectivity and ease of interpretation.
Ben-David, A. (Arie) +2 more
core +1 more source
NKCC1: A key regulator of glioblastoma progression
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Evidence Based Medicine; Receiver Operating Characteristic Curve and Area under the Curve
Multiple diagnostic tools are used by emergency physicians, every day. In addition, new tools are evaluated to obtain more accurate methods and reduce time or cost of conventional ones.
Saeed Safari, Alireza Baratloo
doaj
3D ROC Histogram: A New ROC Analysis Tool Incorporating Information on Instances
While Receiver Operator Characteristic (ROC) curves have been a standard tool in the design and evaluation of binary classification problems, they have sometimes been blamed for ignoring some vital information in the evaluation process, such as predicted
Rui Guo, Xuanjing Shen, Xiaoli Zhang
doaj +1 more source
An Improved Method for Bandwidth Selection when Estimating ROC Curves [PDF]
The receiver operating characteristic (ROC) curve is used to describe the performance of a diagnostic test which classifies observations into two groups.
Peter Hall, Rob J. Hyndman
core
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source

