Results 101 to 110 of about 651,813 (285)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Vulnerability to poverty: An empirical comparison of alternative measures [PDF]

open access: yes
The recent common feeling about a skyrocketing economic risk has drawn increasing attention to its role and consequences on individuals' welfare.
Celidoni, Martina
core   +1 more source

AUK: a simple alternative to the AUC [PDF]

open access: yes, 2010
The area under Receiver Operating Characteristic (ROC) curve, also known as the AUC-index, is commonly used for ranking the performance of data mining models. The AUC has many merits, such as objectivity and ease of interpretation.
Ben-David, A. (Arie)   +2 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Evidence Based Medicine; Receiver Operating Characteristic Curve and Area under the Curve

open access: yesطب اورژانس ایران, 2016
Multiple diagnostic tools are used by emergency physicians, every day. In addition, new tools are evaluated to obtain more accurate methods and reduce time or cost of conventional ones.
Saeed Safari, Alireza Baratloo
doaj  

3D ROC Histogram: A New ROC Analysis Tool Incorporating Information on Instances

open access: yesIEEE Access, 2019
While Receiver Operator Characteristic (ROC) curves have been a standard tool in the design and evaluation of binary classification problems, they have sometimes been blamed for ignoring some vital information in the evaluation process, such as predicted
Rui Guo, Xuanjing Shen, Xiaoli Zhang
doaj   +1 more source

An Improved Method for Bandwidth Selection when Estimating ROC Curves [PDF]

open access: yes
The receiver operating characteristic (ROC) curve is used to describe the performance of a diagnostic test which classifies observations into two groups.
Peter Hall, Rob J. Hyndman
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

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