Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Comparing adiposity-related predictors of cardiometabolic disease in two Indigenous Guatemalan municipalities: a cross-sectional receiver operating characteristic analysis. [PDF]
Alajajian S, Rohloff P.
europepmc +1 more source
Discriminative Evaluation of Sarcopenic Dysphagia Using Handgrip Strength or Calf Circumference in Patients with Dysphagia Using the Area under the Receiver Operating Characteristic Curve. [PDF]
Kishimoto H +3 more
europepmc +1 more source
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar +11 more
wiley +1 more source
Likelihood-Based Non-Parametric Receiver Operating Characteristic Curve Analysis in the Presence of Imperfect Reference Standard. [PDF]
Sun Y, Sang P, Tian Q, Li P.
europepmc +1 more source
The correlation between nutrition and frailty and the receiver operating characteristic curve of different nutritional indexes for frailty. [PDF]
Liang H, Li X, Lin X, Ju Y, Leng J.
europepmc +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Estimation of receiver operating characteristic curve when case and control require different transformations for normality. [PDF]
Cai X, Zhang W, Li H, Li Z, Liu A.
europepmc +1 more source
Receiver operating characteristic curves and confidence bands for support vector machines. [PDF]
Luckett DJ +7 more
europepmc +1 more source
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source

