Results 41 to 50 of about 263,702 (262)

Identifying Potential miRNAs–Disease Associations With Probability Matrix Factorization

Frontiers in Genetics, 2019
In recent years, miRNAs have been verified to play an irreplaceable role in biological processes associated with human disease. Discovering potential disease-related miRNAs helps explain the underlying pathogenesis of the disease at the molecular level ...
Junlin Xu, Lijun Cai, Bo Liao, Wen Zhu, Peng Wang, Yajie Meng, Jidong Lang, Geng Tian, Jialiang Yang   +8 more
doaj   +1 more source

Determining the SARS-CoV-2 Anti-Spike Cutoff Level Denoting Neutralizing Activity Using Two Commercial Kits

Vaccines, 2022
Background: The viral neutralization assay is the gold standard to estimate the level of immunity against SARS-CoV-2. This study analyzes the correlation between the quantitative Anti-SARS-CoV-2 QuantiVac ELISA (IgG) and the NeutraLISA neutralization ...
Engy Mohamed El-Ghitany, Mona H. Hashish, Azza Galal Farghaly, Eman A. Omran   +3 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Predicting Customer’s Satisfaction (Dissatisfaction) Using Logistic Regression [PDF]

International Journal of Mathematical, Engineering and Management Sciences, 2016
Customer satisfaction is a metric of how products and services offered by companies meet customer expectations. This performance indicator assists companies in managing and monitoring their business effectively.
Adarsh Anand, Gunjan Bansal
doaj   +1 more source

The establishment and validation of a prediction model for traumatic intracranial injury patients: a reliable nomogram

Frontiers in Neurology, 2023
ObjectiveTraumatic brain injury (TBI) leads to death and disability. This study developed an effective prognostic nomogram for assessing the risk factors for TBI mortality.MethodData were extracted from an online database called “Multiparameter ...
Jia Yi Chen, Jia Yi Chen, Guang Yong Jin, Guang Yong Jin, Long Huang Zeng, Long Huang Zeng, Bu Qing Ma, Bu Qing Ma, Hui Chen, Hui Chen, Nan Yuan Gu, Nan Yuan Gu, Kai Qiu, Kai Qiu, Fu Tian, Fu Tian, Lu Pan, Lu Pan, Wei Hu, Dong Cheng Liang   +19 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Relation of Serum Hepcidin Levels and Restless Legs Syndrome in Patients Undergoing Peritoneal Dialysis

Frontiers in Medicine, 2021
Introduction: Restless legs syndrome is a common and severe complication in patients undergoing peritoneal dialysis (PD), which seriously affects the life quality and prognosis of patients undergoing PD.
Yanhong Guo, Yuan Sang, Tian Pu, Xiaodan Li, Yulin Wang, Lu Yu, Yan Liang, Liuwei Wang, Peipei Liu, Lin Tang   +9 more
doaj   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

An efficient and user-friendly software tool for ordered multi-class receiver operating characteristic analysis based on python

SoftwareX, 2022
Receiver Operating Characteristic (ROC) analysis is a prevalent tool for two-class problems in a wide range of science and engineering areas. The relevant scalar area under the ROC curve (AUC) has been proven to be a robust evaluation index for ...
Shun Liu, Junjie Yang, Xianxian Zeng, Haiying Song, Jian Cen, Weichao Xu   +5 more
doaj   +1 more source