Results 61 to 70 of about 263,702 (262)

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Assessment of Sonoelastography as Diagnosis Tool of Inflammatory Myopathies [PDF]

open access: yesApplied Medical Informatics, 2010
Background: Inflammatory myopathies represent a special group of pathology. Establishing the correct diagnosis in the early phase and a better follow-up are the main objective for improving the life quality of these patients.
Carolina BOTAR-JID   +6 more
doaj  

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang   +4 more
wiley   +1 more source

Image saliency detection based on geodesic‐like and boundary contrast maps

open access: yesETRI Journal, 2019
Image saliency detection is the basis of perceptual image processing, which is significant to subsequent image processing methods. Most saliency detection methods can detect only a single object with a high‐contrast background, but they have no effect on
Yingchun Guo, Yi Liu, Runxin Ma
doaj   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi   +17 more
wiley   +1 more source

On Boundary Correction in Kernel Estimation of ROC Curves

open access: yesAustrian Journal of Statistics, 2016
The Receiver Operating Characteristic (ROC) curve is a statistical tool for evaluating the accuracy of diagnostics tests. The empirical ROC curve (which is a step function) is the most commonly used non-parametric estimator for the ROC curve.
Jan Koláček, Rohana J. Karunamuni
doaj   +1 more source

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma   +16 more
wiley   +1 more source

Robust volcano plot: identification of differential metabolites in the presence of outliers

open access: yesBMC Bioinformatics, 2018
Background The identification of differential metabolites in metabolomics is still a big challenge and plays a prominent role in metabolomics data analyses.
Nishith Kumar   +2 more
doaj   +1 more source

Diagnostic Use of Testing for Novel Murine Autoantibodies for Sjögren Disease in the Rheumatology Outpatient Setting

open access: yesArthritis Care &Research, EarlyView.
Objective The goal was to assess the diagnostic performance of three novel autoantibodies (NA) for Sjögren disease (SjD) by comparing NA prevalence in patients with SjD, other autoimmune rheumatic diseases (ARDs), nonspecific chronic sialadenitis (CS), and controls.
Chadwick R. Johr   +5 more
wiley   +1 more source

The influence of tinnitus acceptance on the quality of life and psychological distress in patients with chronic tinnitus

open access: yesNoise and Health, 2015
Recent findings show the importance of acceptance in the treatment of chronic tinnitus. So far, very limited research investigating the different levels of tinnitus acceptance has been conducted.
David Riedl   +5 more
doaj   +1 more source

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