Results 91 to 100 of about 310,651 (297)

ELABELA Targets Mitochondria to Modulate Heart Development

Advanced Science, EarlyView.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang, Qingjie Wang, Zhikang Xu, Shuang Zhou, Yue Zhou, Junjie Yang, Lingfeng Tong, Zhuo Meng, Mei Yang, Wen Zhao, Tie Yang, Hualin Wang, Jun Zhang, Rubin Tan, Lei Wang, Yuqiang Huang, Bin Zhou, Sun Chen, Bing Zhang, Jinxiang Yuan, Jianyuan Zhao, Alex F. Chen, Kun Sun   +22 more
wiley   +1 more source

The influence of tinnitus acceptance on the quality of life and psychological distress in patients with chronic tinnitus

Noise and Health, 2015
Recent findings show the importance of acceptance in the treatment of chronic tinnitus. So far, very limited research investigating the different levels of tinnitus acceptance has been conducted.
David Riedl, Gerhard Rumpold, Annette Schmidt, Patrick G Zorowka, Harald R Bliem, Roland Moschen   +5 more
doaj   +1 more source

Receiver-operating characteristic (ROC) curves (total study cohort) for ELF and previously published algorithms developed in NAFLD patients.

, 2016
Receiver-operating characteristic (ROC) curves (total study cohort) for ELF and previously published algorithms developed in NAFLD patients.
Byron Lykiardopoulos (3391277), Hannes Hagström (602237), Per Stål (2219593), Mattias Ekstedt (602234), Mats Fredrikson (224175), Stergios Kechagias (602235), Simone Ignatova (3391274), Rolf Hultcrantz (602236)   +7 more
core   +1 more source

Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1

Advanced Science, EarlyView.
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency, Tao Cui, Yimei Cai, Chloe Lok, Rachel E. Nokku, Ruoxian Huang, Grace L. Chu, Yumeng Xie, Saleem W. Abu‐Tayeh, Kaikai He, Chengjie Qiu, Junyi Wang, Paxton M. Paganelli, Ting Wang, Gabrielle Williams, Sreejith Nair, Huadong Pei, Dion K. Dickman, Stefano Vicini, Tingting Wang   +19 more
wiley   +1 more source

Receiver-operating characteristic (ROC) curves (total study cohort) for previously published algorithms developed in patients with hepatitis C virus infection.

, 2016
Receiver-operating characteristic (ROC) curves (total study cohort) for previously published algorithms developed in patients with hepatitis C virus infection.
Byron Lykiardopoulos (3391277), Hannes Hagström (602237), Per Stål (2219593), Mattias Ekstedt (602234), Mats Fredrikson (224175), Stergios Kechagias (602235), Simone Ignatova (3391274), Rolf Hultcrantz (602236)   +7 more
core   +1 more source

Causal Prediction of TP53 Variant Pathogenicity Using a Perturbation‐Informed Protein Language Model

Advanced Science, EarlyView.
A TP53‐specific predictor, CaVepP53, is developed by fine‐tuning ESMC on experimentally validated variants, quantifying pathogenicity via Euclidean distances. It outperforms general‐purpose models and extends to five cancer genes, enabling interpretable variant classification for precision medicine.
Huiying Chen, Yang Zhao, Boqiang Hu, Wuke Wang, Minfang Song, Annabeth Xinyu Zhao, Xiangyang Li, Gefei Wang, Yanfen Wang, Weiyan Zheng, Xinpeng Zhang, Xia Lin, Yanbin Yin, Xingxu Huang, Jinfang Zheng, Tingbo Liang   +15 more
wiley   +1 more source

Tutorial on Biostatistics: Receiver-Operating Characteristic (ROC) Analysis for Correlated Eye Data. [PDF]

Ophthalmic Epidemiol, 2022
Ying GS, Maguire MG, Glynn RJ, Rosner B.
europepmc   +1 more source

The Classification of Economic Activity into Expansions and Recessions [PDF]

The Business Cycle Dating Committee (BCDC) of the National Bureau of Economic Research provides a historical chronology of business cycle turning points. This paper investigates three central aspects about this chronology: (1) How skillful is the BCDC in
Oscar Jorda, Travis Berge
core  

Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome

Advanced Science, EarlyView.
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu, Shuhao Chen, Yunheng Diao, Wei Wang, Yuanyuan Huang, Liqin Liang, Xiaodan Lu, Rui Han, Minxin Guo, Zhaobo Li, Shuhong Wang, Hehua Li, Chenyu Liu, Jing Zhou, Dongsheng Xiong, Xiaobo Li, Yuping Ning, Xuetao Shi, Fengchun Wu, Kai Wu   +19 more
wiley   +1 more source

It is a misunderstanding that log ratio outperforms ratio in change detection of SAR images

European Journal of Remote Sensing, 2019
Ratio and log ratio operators were widely used in change detection of synthetic aperture radar (SAR) images. It is well known for the researchers who focus on change detection of SAR images that log ratio outperforms ratio because logarithmic ...
Huifu Zhuang, Zhixiang Tan, Kazhong Deng, Hongdong Fan   +3 more
doaj   +1 more source