Results 111 to 120 of about 310,651 (297)

Legumain Restrains Granuloma Formation by Inhibiting mTORC1/STAT1‐Mediated M1 Macrophage Polarization in Sarcoidosis

Advanced Science, EarlyView.
Legumain (LGMN) is upregulated in macrophages during sarcoid‑like granuloma formation. Macrophage‑derived LGMN binds to integrin αvβ3 and suppresses mTORC1/STAT1 signaling to restrain M1 macrophage polarization. Intratracheal delivery of lipid nanoparticles carrying Lgmn plasmid DNA (pDNA) elevates LGMN expression and effectively attenuates pulmonary ...
Mengyuan Liu, Yueyin Han, Bingbing Xie, Lili Zhu, Wenxiu Xu, Yinzhen Han, Yue Liao, Shuwei Gao, Dingyuan Jiang, Jing Geng, Zhen Li, Yinan Hu, Huaping Dai   +12 more
wiley   +1 more source

Receiver operating characteristic (ROC) curve for Crohn’s disease patients.

, 2019
Receiver operating characteristic (ROC) curve for Crohn’s disease patients.
Emily Brandt (7244525), Kevin J. Dombkowski (7244531), Jeremy Adler (655530), Jessica K. Haraga (7244528), Hannah K. Jary (7244516), Shiming Dong (7244522), Sally J. Eder (7244519)   +6 more
core   +1 more source

A Bioinspired Three‐Dimensional High‐Curvature Nano‐Interface Integrated Microfluidic Chip for Small Extracellular Vesicles Enrichment and Machine Learning‐Assisted Prostate Cancer Precision Diagnosis

Advanced Science, EarlyView.
A biotin‐modified artificial insertion peptide functionalized three‐dimensional high‐curvature‐TiO2 nano‐interface was engineered in a microfluidic chip to improve the isolation efficiency of small extracellular vesicles (sEVs). This chip balanced affinity, releasability, and extendibility, enabling high‐throughput recovery of sEVs for downstream ...
Le Wang, Yizhong Liang, Manan Sulaiman, Jiaqi Du, Ming Jiang, Zhihua Wang, Xu Yu, Li Xu   +7 more
wiley   +1 more source

Anthropometric cutoff values for detecting metabolic abnormalities in Jordanian adults

Diabetes, Metabolic Syndrome and Obesity, 2010
Yousef S Khader1, Anwar Batieha1, Hashim Jaddou1, Zahi Batieha2, Mohammed El-Khateeb3, Kamel Ajlouni31Department of Community Medicine, Public Health and Family Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan ...
Khader Y, Batieha A, Yousef H, El-Khateeb M, Ajlouni K, Zahi Batieha   +5 more
doaj  

Receiver-operating characteristic (ROC) curve of EuroSCORE models.

, 2015
Receiver-operating characteristic (ROC) curve of EuroSCORE models.
Pablo M. Pomerantzeff (695966), Roney Sampaio (695965), Marcelo Katz (695963), Antonio Bacelar (695964), Otavio T. Ranzani (388498), Max Grinberg (174137), Ricardo Casalino (695960), Flávio Tarasoutchi (695961), Guilherme Spina (695962)   +8 more
core   +1 more source

Small Extracellular Vesicles‐Derived Circ6718 Unlocks Stromal Remodeling and Serves as a Biomarker in Gastric Cancer

Advanced Science, EarlyView.
sEVs‐circ6718 serves as a promising serum biomarker for gastric cancer early diagnosis and prognosis, promoting malignant transformation in gastric cancer cells and GC‑MSC differentiation into CAFs. sEVs‑circ6718 holds potential as a biomarker for the early diagnosis and prognostic assessment of gastric cancer.
Fan Zhang, Xueyan Zang, Dongli Wang, Rong Li, Hui Qian, Wenrong Xu, Jiajia Jiang, Yongmin Yan   +7 more
wiley   +1 more source

Estimating the Area under a Receiver Operating Characteristic Curve For Repeated Measures Design

The receiver operating characteristic (ROC) curve is widely used for diagnosing as well as for judging the discrimination ability of different statistical models.
Honghu Liu, Tongtong Wu
core  

FASLG Derived from Fibroblasts in Hydroxyapatite‐Rich Microenvironment Induces Urothelial Anoikis to Trigger Randall's Plaque Exposure

Advanced Science, EarlyView.
Randall's plaques (RP) serve as the nidus for calcium oxalate (CaOx) kidney stones. The current study reveals that hydroxyapatite (HAP) crystals activate the THY1–GSK3α/β–β‐catenin axis in renal interstitial fibroblasts (hRIFs), inducing FASLG secretion.
Minghui Liu, Maolan Wu, Meng Gao, Yongchao Li, Miao Yuan, Zhangcheng Liao, Zhi Liu, Yizhou Wang, Yu Cui, Jinbo Chen, Cheng He, Zhiyong Chen, Feng Zeng, Hequn Chen, Zewu Zhu   +14 more
wiley   +1 more source

Using milk components to estimate the risk of energy imbalance in Holstein cows by means of receiver operating characteristic (ROC) analysis

Czech Journal of Animal Science
Negative energy balance (NEB) in dairy cows during early lactation significantly contributes to metabolic and infectious diseases, traditionally diagnosed via costly and time-consuming serum non-esterified fatty acids (NEFA) analysis. This study aimed to 
Magdaléna Štolcová, Luděk Bartoň, Eva Kašná   +2 more
doaj   +1 more source

Flood vulnerability mapping using frequency ratio (FR) model: a case study on Kulik river basin, Indo-Bangladesh Barind region

Applied Water Science, 2019
Flood is a natural but inevitable phenomenon occurring over the period of time. It not only damages the life, property and resources, but also hampers the economy of a nation. In this paper, an attempt has been made to delineate flood vulnerability areas
Debabrata Sarkar, Prolay Mondal
doaj   +1 more source