Results 31 to 40 of about 280,956 (255)

Psychometric Properties of the Persian Version Post-Stroke Depression Scale: The Case of Neurology Outpatients in Rasht, North Iran

Caspian Journal of Neurological Sciences, 2020
Background: Psychiatrists use different scales to evaluate post-stroke depression; however, some concerns have raised about their low specificity. Objectives: This study aimed to assess the validity and reliability of the Persian version of the Post ...
Somayeh Shokrgozar, Maryam Alizade Nia, Robabeh Soleimani, Mahnaz Fallahi Kheshtmasjedi, Sareh Maadi Raad, Aida Yahyazadeh   +5 more
doaj  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Understanding receiver operator characteristic (ROC) curves

New Zealand Medical Student Journal, 2019
Receiver operating characteristic (ROC) curves summarise graphically the trade-off between sensitivity and specificity for diagnostic tests.1 We will describe how to interpret these graphs, but first we need to understand how we assess diagnostic test accuracy and why we are interested in these concepts of sensitivity and specificity.
Robin M Turner, Claire Cameron, Ari Samaranayaka   +2 more
openaire   +2 more sources

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Automated Detection of Driver Fatigue Based on AdaBoost Classifier with EEG Signals

Frontiers in Computational Neuroscience, 2017
Purpose: Driving fatigue has become one of the important causes of road accidents, there are many researches to analyze driver fatigue. EEG is becoming increasingly useful in the measuring fatigue state. Manual interpretation of EEG signals is impossible,
Jianfeng Hu
doaj   +1 more source

ROC Solid: Receiver Operator Characteristic (ROC) Curves as a Foundation for Better Diagnostic Tests [PDF]

Global Spine Journal, 2018
An ROC curve describes the relationship between the sensitivity and specificity of a test by plotting the two against one another while varying the CV. It is helpful when the outcome of a diagnostic test is continuous or ordinal. The key to an effective diagnostic test is to accurately classify 2 distinct populations into their respective groups ...
Junge, Mark R. J., Dettori, Joseph R.
openaire   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Treatment of adult facial asymmetry with orthodontic therapy or orthognathic surgery: Receiver operating characteristic analysis

Journal of Dental Sciences, 2014
Background/purpose: Not all adult facial asymmetry patients are candidates for surgical correction, therefore patient assessment and selection remain major issues in diagnosis and treatment planning.
Yu-Chuan Tseng, Yi-Hsin Yang, Chin-Yun Pan, Szu-Ting Chou, Kai-Chieh Ou, Hong-Po Chang   +5 more
doaj   +1 more source

Combining total and differential somatic cell count to screen for mastitis [PDF]

Acta Fytotechnica et Zootechnica, 2020
Somatic cell count (SCC) has been extensively used as indicator of udder health and milk quality. Recent developments in milk-testing technology have led to cell differentiation in milk in a high throughput manner.
Tania Bobbo
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source