Results 41 to 50 of about 3,064,133 (295)

ROC Solid: Receiver Operator Characteristic (ROC) Curves as a Foundation for Better Diagnostic Tests [PDF]

Global Spine Journal, 2018
An ROC curve describes the relationship between the sensitivity and specificity of a test by plotting the two against one another while varying the CV. It is helpful when the outcome of a diagnostic test is continuous or ordinal. The key to an effective diagnostic test is to accurately classify 2 distinct populations into their respective groups ...
Junge, Mark R. J., Dettori, Joseph R.
openaire   +2 more sources

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Treatment of adult facial asymmetry with orthodontic therapy or orthognathic surgery: Receiver operating characteristic analysis

Journal of Dental Sciences, 2014
Background/purpose: Not all adult facial asymmetry patients are candidates for surgical correction, therefore patient assessment and selection remain major issues in diagnosis and treatment planning.
Yu-Chuan Tseng, Yi-Hsin Yang, Chin-Yun Pan, Szu-Ting Chou, Kai-Chieh Ou, Hong-Po Chang   +5 more
doaj   +1 more source

Understanding receiver operator characteristic (ROC) curves

New Zealand Medical Student Journal, 2019
Receiver operating characteristic (ROC) curves summarise graphically the trade-off between sensitivity and specificity for diagnostic tests.1 We will describe how to interpret these graphs, but first we need to understand how we assess diagnostic test accuracy and why we are interested in these concepts of sensitivity and specificity.
Robin M Turner, Claire Cameron, Ari Samaranayaka   +2 more
openaire   +2 more sources

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Min-Max, Min-Max-Median, and Min-Max-IQR in Deciding Optimal Diagnostic Thresholds: Performances of a Logistic Regression Approach on Simulated and Real Data

Applied Medical Informatics, 2023
Combining biomarkers and their statistics is used to increase the prediction performance of a diagnosis, but no gold standard method exists. We introduced and evaluated an approach using linear combinations of summary-based statistics tested in logistic ...
Ilie-Andrei CONDURACHE, Sorana D. BOLBOACĂ   +1 more
doaj  

On the Binormal Predictive Receiver Operating Characteristic Curve for the Joint Assessment of Positive and Negative Predictive Values

Entropy, 2020
The predictive receiver operating characteristic (PROC) curve is a diagrammatic format with application in the statistical evaluation of probabilistic disease forecasts.
Gareth Hughes
doaj   +1 more source

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

Aging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara, Takashi Kawahara, Kazuhide Makiyama, Hiroji Uemura   +3 more
wiley   +1 more source