Results 41 to 50 of about 393,760 (288)
European Journal of Medical Research, 2022 Background Current biomarkers for the early detection of sepsis have low sensitivity and specificity. Serum microRNAs (miRNAs) have been proposed as novel noninvasive biomarkers for various diseases.
Zhaorui Zhang +3 more
doaj +1 more source
Abnormal attentions towards the British Royal Family. Factors associated with approach and escalation [PDF]
, 2010 Abnormal approach and escalation from communication to physical intrusion are central concerns in managing risk to prominent people. This study was a retrospective analysis of police files of those who have shown abnormal attentions toward the British ...
Calhoun +27 more
core +1 more source
Pain detection with bioimpedance methodology from 3-dimensional exploration of nociception in a postoperative observational trial [PDF]
, 2020 Although the measurement of dielectric properties of the skin is a long-known tool for assessing the changes caused by nociception, the frequency modulated response has not been considered yet.
Copot, Dana +4 more
core +1 more source
Multicenter Validation of the Vasoactive-Ventilation-Renal Score as a Predictor of Prolonged Mechanical Ventilation After Neonatal Cardiac Surgery [PDF]
, 2018 Objectives: We sought to validate the Vasoactive-Ventilation-Renal score, a novel disease severity index, as a predictor of outcome in a multicenter cohort of neonates who underwent cardiac surgery. Design: Retrospective chart review.
Cashen, Katherine +7 more
core +1 more source
ROCS: receiver operating characteristic surface for class-skewed high-throughput data. [PDF]
PLoS ONE, 2012 The receiver operating characteristic (ROC) curve is an important tool to gauge the performance of classifiers. In certain situations of high-throughput data analysis, the data is heavily class-skewed, i.e.
Tianwei Yu
doaj +1 more source
Molecular Oncology, Volume 20, Issue 6, Page 1473-1493, June 2026.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Acute kidney injury prediction in cardiac surgery patients by a urinary peptide pattern: a case-control validation study [PDF]
, 2016 Background Acute kidney injury (AKI) is a prominent problem in hospitalized patients and associated with increased morbidity and mortality. Clinical medicine is currently hampered by the lack of accurate and early biomarkers for diagnosis of AKI and the
Groesdonk, Heiner +7 more
core +3 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Czech Journal of Animal ScienceNegative energy balance (NEB) in dairy cows during early lactation significantly contributes to metabolic and infectious diseases, traditionally diagnosed via costly and time-consuming serum non-esterified fatty acids (NEFA) analysis. This study aimed to
Magdaléna Štolcová +2 more
doaj +1 more source
A Linear Regression Framework for Receiver Operating Characteristic(ROC) Curve Analysis [PDF]
, 2005 In the field of medical diagnostic testing, the receiver operating characteristics(ROC) curve has long been used as a standard statistical tool to assess the accuracy of tests that yield continuous results. Although previous research in this area focused
Pepe, Margaret S., Zhang, Zheng
core +1 more source