Results 51 to 60 of about 393,760 (288)

Serum micrornas as novel biomarkers for primary sclerosing cholangitis and cholangiocarcinoma [PDF]

, 2016
The diagnosis of primary sclerosing cholangitis (PSC) is difficult due to the lack of sensitive and specific biomarkers, as is the early diagnosis of cholangiocarcinoma (CC), a complication of PSC.
Alpini, Gianfranco, Alvaro, Domenico, Bernuzzi, Francesca, Bowlus, Christopher L, Carbone, Marco, Eric Gershwin, M, He, Xiao Song, Invernizzi, Pietro, Lleo, Ana, Locati, Massimo, Marabita, Francesco, Marzioni, Marco, Mirolo, Massimiliano, Muri Boberg, Kirsten, Piscaglia, Fabio, Rimassa, Lorenza, Torzilli, Guido, Yang, Guo Xiang   +17 more
core   +2 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

The impact of computed high b-value images on the diagnostic accuracy of DWI for prostate cancer: A receiver operating characteristics analysis. [PDF]

, 2018
To evaluate the performance of computed high b value diffusion-weighted images (DWI) in prostate cancer detection. 97 consecutive patients who had undergone multiparametric MRI of the prostate followed by biopsy were reviewed.
Daniel, Bruce L, Fan, Richard E, Ghanouni, Pejman, Hargreaves, Brian A, Loening, Andreas M, Ning, Peigang, Obara, Piotr, Shi, Dapeng, Shin, Lewis K, Sonn, Geoffrey A, Vasanawala, Shreyas S   +10 more
core   +2 more sources

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

QUANTITATIVE ANALYSIS OF LIVER IRON DEPOSITION BASED ON DUAL-ENERGY CT IN THALASSEMIA PATIENTS

Mediterranean Journal of Hematology and Infectious Diseases, 2023
Objective: To explore the feasibility and accuracy of liver iron deposition based on dual-energy CT in thalassemia patients. Materials and methods: 105 thalassemia patients were examined with dual-energy CT and MR liver scanning.
Fengming Xu, Cheng Tang, Yiling Huang, Linlin Liang, Fuling Huang, Gaohui Yang, Peng Peng   +6 more
doaj   +1 more source

Estimation and Comparison of Receiver Operating Characteristic Curves [PDF]

, 2008
The receiver operating characteristic (ROC) curve displays the capacity of a marker or diagnostic test to discriminate between two groups of subjects, cases versus controls.
Janes, Holly, Longton, Gary M., Pepe, Margaret   +2 more
core   +1 more source

The Positive Thinking Skills Scale: A Screening Measure for Early Identification of Depressive Thoughts [PDF]

, 2017
Background Depression is currently considered the second leading cause of disability worldwide. Positive thinking is a cognitive process that helps individuals to deal with problems more effectively, and has been suggested as a useful strategy for coping
Bekhet, Abir K., Garnier-Villarreal, Mauricio   +1 more
core   +2 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

ESSENCE-Q – a first clinical validation study of a new screening questionnaire for young children with suspected neurodevelopmental problems in south Japan

Neuropsychiatric Disease and Treatment, 2016
Yuhei Hatakenaka,1,2 Elisabeth Fernell,2 Masahiko Sakaguchi,3 Hitoshi Ninomiya,3 Ichiro Fukunaga,1 Christopher Gillberg2 1Kochi Gillberg Neuropsychiatry Centre, Kochi Prefectural Medical and Welfare Centre, Kochi, Japan; 2Gillberg Neuropsychiatry Centre,
Hatakenaka Y, Fernell E, Sakaguchi M, Ninomiya H, Fukunaga I, Gillberg C   +5 more
doaj