FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Henricus Reneri (1593-1639). Descartes’ Quartermaster in Aristotelian Territory
, 2013 This study provides an overview of the life and work of the seventeenth-century Utrecht professor of philosophy Henricus Reneri, with special focus on his close relationship with René Descartes. Reneri met Descartes during the winter of 1628/29.
LS FAC Verbeek +4 more
core
Wirkungsgeschichte, Reception History, Reception Theory
, 2010 In an attempt to introduce Wirkungsgeschichte, reception history and reception theory, this article begins by considering the different histories each term carries.
Mark Knight, Knight, Mark James
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Philosophy, Scientific Knowledge, and Concept Formation in Geulincx and Descartes
, 2010 Descartes does not have an elaborated theory of scientific knowledge. His academic followers, however, needed that to construct a comprehensive philosophy. One of the more interesting Cartesians was Arnout Geulincx (1624-1669).
Aalderink, M.J.H. +2 more
core
Lee Rothfarb and Christoph Landerer, Eduard Hanslick’s ‘On the Musically Beautiful’: A New Translation, New York: Oxford University Press 2018 / Alexander Wilfing, Re-Reading Hanslick’s Aesthetics: Die Rezeption Eduard Hanslicks im englischen Sprachraum und ihre diskursiven Grundlagen (= Wiener Veröffentlichungen zur Musikwissenschaft, Bd. 49), Wien: Hollitzer 2019 [PDF]
Zeitschrift der Gesellschaft für Musiktheorie, 2021 Benedict Taylor
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Making a Transnational Design History in East Asia: Yen Shuilong’s Craft-Design Movement [PDF]
, 2013 Yen Shuilong (1903-97) was born in Taiwan within the ‘Japanese Empire’ but his live is dominated by what we would now call transnational activities. During the fifteen years since his death, there have been a number of retrospective exhibitions on him ...
Kikuchi, Yuko
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source