Results 191 to 200 of about 42,145 (224)
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Oncology Reports, 2004
Endothelin-1 (ET-1) is overexpressed in breast carcinomas and influences via its receptors (ETAR and ETBR) transformation, differentiation and growth processes in the human breast, but little is known about the ET expression in breast cancer precursors.
Pia, Wülfing +7 more
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Endothelin-1 (ET-1) is overexpressed in breast carcinomas and influences via its receptors (ETAR and ETBR) transformation, differentiation and growth processes in the human breast, but little is known about the ET expression in breast cancer precursors.
Pia, Wülfing +7 more
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Mutations of the endothelin-B receptor and endothelin-3 genes in Hirschsprung?s disease
Pediatric Surgery International, 1996The endothelin-B receptor gene (EDNRB) and the endothelin-3 gene (EDN3) have recently been recognized as susceptibility genes for Hirschsprung's disease (HD). Novel EDNRB mutations have been detected in non-syndromic HD patients with heterozygous forms, and homozygous mutations of the EDNRB or the EDN3 genes have been reported in HD patients associated
T, Kusafuka, P, Puri
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Antidiuretic effects of endothelin B receptor antagonism
The FASEB Journal, 2008Activation of endothelin (ET)‐B receptors has diuretic and natriuretic effects. Whether these effects are mediated by renal hemodynamic mechanisms or by renal tubular inhibition of salt and water reabsorbtion is unclear. We tested the hypothesis that systemic administration of ET‐B receptor antagonist (BQ‐788) at concentrations devoid of renal ...
Radu Iliescu, Ovidiu Constantin Baltatu
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Endothelin and Endothelin A/B Receptors Are Increased after Ischaemic Acute Renal Failure
Nephron Experimental Nephrology, 2001<i>Background/Aims:</i> Endothelin (ET) has been implicated as an indirect mediator of injury following acute renal ischaemia (ARI). The purpose of this study was to localize and quantitate ET and ET<sub>A</sub> and ET<sub>B</sub> receptors following ARI. <i>Methods:</i> A model of ARI, well characterized
Forbes, JM +5 more
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Endothelin-B receptor-mediated Ca
Pflügers Archiv, 1998Hee-Young Kang +2 more
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[Endothelin B receptor system and Hirschsprung disease].
Nihon rinsho. Japanese journal of clinical medicine, 1998Hirschsprung disease is a congenital malformation caused by the absence of ganglion cells in the myenteric and submucosal neural plexuses of gut. Mutations in the endothelin-Beta receptor (EDNRB) and endothelin-3(EDN3) genes as well as in the RET, glial-cell-derived neurotrophic factor and sox 10 genes have been shown to be responsible for this disease.
M, Inoue, T, Kusafuka, A, Okada
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Role of endothelin b receptor signals in reactive astrocytes
Life Sciences, 1998We investigated the involvement of endothelinB receptor signals in the activation of astrocytes in vitro and in vivo. Endothelin reversed the stellate morphology of astrocytes induced by several agents. Endothelin stimulates astrocytic stress fiber formation.
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Introduction to Endothelin-3/Endothelin-B Receptor and SOX10 Signaling Pathways
2008Abstract Hirschsprung disease [congenital absence of the distal enteric nervous system (ENS)] and Waardenburg syndrome (pigment abnormalities and sensorineural deafness) result from abnormal embryonic development of neural crest (NC)-derived cells.
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