Results 1 to 10 of about 66,252 (120)
Biomedicines, 2021 The endothelium is the single-cell monolayer that lines the entire vasculature. The endothelium has a barrier function to separate blood from organs and tissues but also has an increasingly appreciated role in anti-coagulation, vascular senescence ...
Peter J. Little +3 more
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Cells, 2023 Glioblastoma (GBM) is the most common and aggressive type of brain tumor due to its elevated recurrence following treatments. This is mainly mediated by a subpopulation of cells with stemness traits termed glioblastoma stem-like cells (GSCs), which are ...
Ignacio Niechi +17 more
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Endothelin-1 level as a predictor of hepatopulmonary syndrome in liver cirrhosis [PDF]
Medicinski Glasnik, 2020 Aim To determine the role of endothelin (ET)-1 in predicting hepatopulmonary syndrome (HPS) in patients with liver cirrhosis. Methods A cross sectional study involving 80 liver cirrhosis patients aged 18 years or older was conducted in Adam Malik ...
Darmadi, Riska Habriel Ruslie
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Bosentan, a drug used in the treatment of pulmonary hypertension, can prevent development of osteoporosis [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): We examined the antiosteoporotic effect of bosentan (Bose) by radiographic, histopathological, and molecular methods.Materials and Methods: Rats were divided into 4 groups of 8 rats each: one control (Sham), one osteoporosis only (OP), and ...
Duygu Köse +6 more
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ET-1 as a Sex-Specific Mechanism Impacting Age-Related Changes in Vascular Function
Frontiers in Aging, 2021 Aging is a primary risk factor for cardiovascular disease (CVD), which is the leading cause of death in developed countries. Globally, the population of adults over the age of 60 is expected to double by the year 2050.
Andrew V. Kuczmarski +4 more
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Gnaq and Gna11 in the Endothelin signaling pathway and melanoma
Frontiers in Genetics, 2016 In this article, we first briefly outline the function of G protein coupled receptors in cancer, and then specifically examine the roles of the seven transmembrane G protein coupled Endothelin B receptor (Ednrb) and the G proteins, GNAQ and GNA11, in ...
Oscar eUrtatiz +1 more
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Immune Mechanisms Linking Obesity and Preeclampsia
Biomolecules, 2015 Preeclampsia (PE) is characterized by hypertension occurring after the twentieth week of pregnancy. It is a significant contributor to maternal and perinatal morbidity and mortality in developing countries and its pervasiveness is increasing within ...
Frank T. Spradley +2 more
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Endothelin-1 in systemic sclerosis
Indian Dermatology Online Journal, 2012 Introduction: Scleroderma is a systemic disorder with unknown etiology most notably characterized by skin thickening and organ damage. Endothelin-1 (ET-1) plays a role in skin fibrosis.
Mehrdad Aghaei +7 more
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Bagcilar Medical Bulletin, 2020 Objective:This study aimed to determine the changes in endothelin and von Willebrand factor (vWF) serum levels during early period aneurysmal subarachnoid hemorrhage (SAH) compared to healthy individuals and to analyze them according to clinical and ...
Serkan Kitiş +2 more
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Transient Mesenteric Ischemia Leads to Remodeling of Rat Mesenteric Resistance Arteries
Frontiers in Physiology, 2012 Mesenteric ischemia/reperfusion (I/R) is associated with high rates of morbidity and mortality. We studied the effect of mesenteric I/R on structural and mechanical properties of rat mesenteric resistance artery (MRA) that, once disrupted, might impact ...
Laura eCaracuel +5 more
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