Results 31 to 40 of about 394,846 (264)
Major Histocompatibility Complex (MHC) molecules have been proposed to play a role in Sickle Cell Disease (SCD) pathophysiology. Endothelial cells express MHC molecules following exposure to cytokines.
Yaritza Inostroza-Nieves+6 more
doaj +1 more source
Prurigo nodularis is a highly pruritic and hyperplastic chronic dermatosis with unknown pathogenesis. Many pruritogenic mediators, including nerve growth factor, interleukin (IL)-31, thymic stromal lymphopoietin, and endothelin-1, are implicated in ...
Weilong Zhong+9 more
doaj +1 more source
Endothelins and liver cirrhosis
Endothelins are a family of 21‐amino acid oligopeptides, called endothelin‐1 (ET‐1), endothelin‐2 (ET‐2), and endothelin 3 (ET‐3). Endothelins act on hepatocytes, liver endothelial cells, and Kupffer cells in a paracrine or autocrine manner through two G
Necati Örmeci
doaj +1 more source
Portopulmonary hypertension practice patterns after liver transplantation
Abstract Portopulmonary hypertension (POPH) is a type of pulmonary arterial hypertension occurring exclusively in those with portal hypertensive liver disease. Liver transplantation (LT) can significantly improve outcomes. Current guidelines counsel against immediate adjustments to targeted therapy after LT and suggest routine echocardiography as ...
Arun Jose+3 more
wiley +1 more source
Endothelin signalling mediates experience-dependent myelination in the CNS
Experience and changes in neuronal activity can alter CNS myelination, but the signalling pathways responsible remain poorly understood. Here we define a pathway in which endothelin, signalling through the G protein-coupled receptor endothelin receptor B
Matthew Swire+4 more
doaj +1 more source
Bioinformatics analysis identifies key genes of prognostic value in lung cancer [PDF]
Lung cancer is the most common human malignancy worldwide and can be divided into different types of carcinomas depending on their pathological features.
Dan Song, Li Sun
doaj +1 more source
Endothelin B receptor (ETBR) is a G protein-coupled receptor able to bind equally to the three identified human endothelin peptides. It is expressed primarily on vascular endothelial cells and involved in various physiological processes including ...
B. Allard+8 more
semanticscholar +1 more source
Endothelin-1 is associated with fibrosis in proliferative diabetic retinopathy membranes. [PDF]
To characterize the relationship between endothelin-1 and fibrosis in epiretinal membranes in proliferative diabetic retinopathy and explore the role of endothelial-mesenchymal transition in these membranes.Membranes were obtained from eyes undergoing ...
William Chang+2 more
doaj +1 more source
Background:The endothelin axis has been shown to have a pivotal role in several human malignancies. The aim of this study was to clarify the clinical importance of endothelin receptor type B (ETBR) in human oesophageal squamous cell carcinoma (OSCC ...
Tetsuya Tanaka+8 more
semanticscholar +1 more source
Downregulation of Endothelin B Receptors in Cardiomyopathic Hamsters
The mechanisms responsible for abnormal fluid retention in congestive heart failure (CHF) are unclear. Studies were conducted to elucidate how endothelin (ET) may contribute to salt and water retention. Cardiomyopathic (CM) hamsters with moderate heart failure were employed for in vivo and in vitro trials.
Wendy H.Y. Wong+4 more
openaire +3 more sources