Results 1 to 10 of about 38,291 (147)

The biochemistry of melanogenesis: an insight into the function and mechanism of melanogenesis-related proteins

Frontiers in Molecular Biosciences
Melanin is an amino acid derivative produced by melanocyte through a series of enzymatic reactions using tyrosinase as substrate. Human skin and hair color is also closely related to melanin, so understanding the mechanisms and proteins that produce ...
Feifei Wang, Feifei Wang, Feifei Wang, Feifei Wang, Wenjing Ma, Wenjing Ma, Dongjie Fan, Dongjie Fan, Jing Hu, Jing Hu, Xiaohong An, Xiaohong An, Xiaohong An, Xiaohong An, Zuding Wang, Zuding Wang   +15 more
doaj   +1 more source

ROLE OF MELANOCORTINE RECEPTOR TYPE 1 IN REGULATION OF BRAIN NEURONS

Neuroscience for Medicine and Psychology, 2020
Irina Romanova, Elena Mikhailova, Anastasiia Mikhrina, Elena Seliverstova   +3 more
openaire   +1 more source

Integrated genomic and structural dissection of melanism in Indian leopard (Panthera pardus fusca)

BMC Genomics
Background Melanism in wild felids represents an intriguing evolutionary trait, potentially advantageous under specific ecological conditions, but the genetic basis of this phenotype remains unclear in many populations.
Avijit Ghosh, Sachin Kumar, Paresh Porob, Mukesh Thakur, Malay Shukla, Satish Kumar, Sweta Nidhi, Abhishek Singh   +7 more
doaj   +1 more source

Significant Weight Loss on a Modified Ketogenic Diet and Intermittent Fasting in a Child With Monogenic Obesity: A Case Report

Dr. Sulaiman Al Habib Medical Journal
Melanocortin-4 receptor (MC4R) mutations disrupt body weight homeostasis and the appetite-feedback loop, affecting approximately 1%–6% of the population.
Bushra Hafez, Zainab Alghamdi, Abdullah Alkhani   +2 more
doaj   +1 more source

Naturally Occurring Mutations in the Melanocortin Receptor 3 Gene Are Not Associated with Type 2 Diabetes Mellitus in French Caucasians¹ [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2001
El Habib Hani, Sophie Dupont, Emmanuelle Durand, Christian Dina, Sophie Gallina, Ira Gantz, Philippe Froguel   +6 more
openaire   +1 more source

CREB coactivator CRTC1 in melanocortin‐4 receptor‐expressing cells regulate dietary fat intake

FASEB BioAdvances
Cyclic adenosine monophosphate‐response element‐binding protein‐1‐regulated transcription coactivator‐1 (CRTC1), a cytoplasmic coactivator that translocates to the nucleus in response to cAMP, is associated with obesity. We previously reported that CRTC1
Shigenobu Matsumura, Miyu Fujisawa, Mizuki Fujiwara, Houko Okayama, Miona Marutani, Eri Nousou, Tsutomu Sasaki, Naoki Harada   +7 more
doaj   +1 more source

Microbial Fermentation Potentiates the Multifunctional Skin-Care Activities of Polianthes tuberosa L. Flower Extract: Antioxidant, Anti-Glycation, and Anti-Melanogenic Effects

Cosmetics
Polianthes tuberosa L. (PT) flower extracts exhibit considerable bioactivities, yet their application is often constrained by limited bioavailability and efficacy.
Qiaozhen Li, Hui Zhu, Rubiao Hou, Teng Jiang, Jinhua Li, Xiaodong Yan, Jing Wang   +6 more
doaj   +1 more source

Culling of Black Plumage Chicks Appeared in the Meat-type Okuminokojidori Breeding Hen Using the SNP of the Melanocortin 1-Receptor Gene

Nihon Chikusan Gakkaiho, 2006
MIWA, Mitsuru, INOUE-MURAYAMA, Miho, KATO, Miki, HAYAKAWA, Hiroshi, OGAWA, Masayuki, OTANI, Ken, ITO, Shin’ichi   +6 more
openaire   +2 more sources

Activation of podocyte-specific MC5R signaling by melanocortin therapy protects against THSD7A-associated membranous nephropathy

Translation
Jing Liu, Yan Ge, Lance Dworkin, Rujun Gong   +3 more
doaj   +1 more source

Targeting Peptidergic Systems for Melanoma Treatment. [PDF]

Cancers (Basel)
Sánchez ML, Mehboob R, Coveñas R.
europepmc   +1 more source