Results 231 to 240 of about 58,465 (248)

Muscarinic analgesia is mediated by non-M1 muscarinic receptors

Life Sciences, 1993
Michael D. B. Swedberg, Charles H. Mitch, Preben H. Olesen, Peter D. Suzdak, Franklin Porter Bymaster, David O. Calligaro, Harlan E. Shannon, John S. Ward, Malcolm J. Sheardown, Per Sauerberg   +9 more
openaire   +2 more sources

Pharmacological Characterization of PD151832, an M1 Muscarinic Receptor Agonist

1997
Alzheimer’s disease (AD) is an age-related disorder characterized by progressive neurological impairment. Among neurotransmitters affected, the loss of forebrain cholinergic neurons has been well documented with the results contributing to the idea that therapies based on cholinergic pharmacology would be useful treatments in AD (Bartus et al., 1982 ...
Haile Tecle, William J. Lipinski, Mark R. Emmerling, Michael J. Callahan, Thomas A. Pugsley, Charlotte Raby, Juan C. Jaen, Carolyn J. Spencer, Katharyn Spiegel, Mark R. Brann, Robert E. Davis, Roy D. Schwarz   +11 more
openaire   +2 more sources

M1 muscarinic receptor facilitates cognitive function by interplay with AMPA receptor GluAl subunit

The FASEB Journal, 2018
Lanxue Zhao, Yan-hui Ge, Cai‐Hong Xiong, Ling Tang, Ying-Hui Yan, P. Law, Yu Qiu, Hong-Zhuan Chen   +7 more
semanticscholar   +1 more source

Rational design of partial agonists for the muscarinic m1 acetylcholine receptor.

Journal of Medicinal Chemistry, 2015
Xinyu Chen, J. Klöckner, Janine Holze, Cornelia Zimmermann, W. Seemann, R. Schrage, A. Bock, K. Mohr, C. Tränkle, U. Holzgrabe, Michael Decker   +10 more
semanticscholar   +1 more source

Acute Effects of Muscarinic M1 Receptor Modulation on AβPP Metabolism and Amyloid-β Levels in vivo: A Microdialysis Study

Journal of Alzheimer's Disease, 2015
T. Welt, L. Kulic, S. Hoey, J. Mcafoose, C. Späni, Antonella Santuccione Chadha, A. Fisher, R. Nitsch   +7 more
semanticscholar   +1 more source

A role for the M1 muscarinic receptor in gastrointestinal motility

Journal of Pharmacological and Toxicological Methods, 2019
Stephen Jenkinson, John T. Lazzaro, Betty Pettersen, Lisa Nottebaum, Asser Bassyouni, Jennifer Elizabeth Davoren   +5 more
openaire   +2 more sources

Central muscarinic analgesia is mediated by M1 receptors

European Journal of Pharmacology, 1990
L. Fantetti, M. Malcangio, A. Bartolini, Alberto Giotti, L. Ghelardini, Petra Malmberg-Aiello   +5 more
openaire   +2 more sources

M1 and M2 Muscarinic Receptor Subtypes Regulate Antidepressant-Like Effects of the Rapidly Acting Antidepressant Scopolamine

Journal of Pharmacology and Experimental Therapeutics, 2014
J. Witkin, C. Overshiner, Xia Li, J. Catlow, Graham N. Wishart, D. Schober, Beverly A. Heinz, A. Nikolayev, Vladimir Tolstikov, W. Anderson, Richard E. Higgs, Ming-Shang Kuo, Christian C. Felder   +12 more
semanticscholar   +1 more source

Evidence of muscarinic M1 receptors on human airways

Pharmacological Research Communications, 1988
V. Guarino, E. Marmo, C. Vacca, D. De Santis, Mario Cazzola, V. De Novellis, M. G. Matera   +6 more
openaire   +2 more sources

The muscarinic M1 receptor positive allosteric modulator PQCA improves cognitive measures in rat, cynomolgus macaque, and rhesus macaque

Psychopharmacology, 2012
J. Uslaner, Donnie M Eddins, Vanita Puri, Christopher E. Cannon, J. Sutcliffe, C. S. Chew, Michelle S. Pearson, J. Vivian, Ronald K. Chang, W. Ray, S. Kuduk, M. Wittmann   +11 more
semanticscholar   +1 more source