Results 81 to 90 of about 144,656 (207)
Journal of Affective Disorders ReportsBackground: Depression and suicidal behavior have been linked to increased blood-brain barrier (BBB) permeability. Platelet-derived growth factor receptor beta (PDGFR-β) is widely expressed in pericytes and promotes BBB integrity.
A. Bontidean +5 more
doaj +1 more source
Mini-Review on Targeted Treatment of Desmoplastic Small Round Cell Tumor
Frontiers in Oncology, 2020 Desmoplastic small round cell tumor (DSRCT) is a devastating disease which most commonly affects adolescents, with a male predominance. Despite the best multimodality treatment efforts, most patients will ultimately not survive more than 3–5 years after ...
Tomas S. Bexelius +5 more
doaj +1 more source
Serum protein fingerprinting by PEA immunoassay coupled with a pattern-recognition algorithms distinguishes MGUS and multiple myeloma [PDF]
, 2016 Serum protein fingerprints associated with MGUS and MM and their changes in MM after autologous stem cell transplantation (MM-ASCT, day 100) remain unexplored.
Fillerová, Regina +9 more
core +1 more source
Journal of Cancer Research and Clinical OncologyObjective In advanced ovarian cancer, the majority of patients receive anti-angiogenic treatment with bevacizumab. However, its use is often associated with severe side effects, and not all patients benefit from the therapy.
Annabelle Volk +7 more
doaj +1 more source
Stronger inflammatory/cytotoxic T cell response in women identified by microarray analysis [PDF]
, 2008 Women develop chronic inflammatory autoimmune diseases like lupus more often than men. The mechanisms causing the increased susceptibility are incompletely understood, although estrogen is believed to contribute.
Anura Hewagama +4 more
core +1 more source
International Journal of Oral-Medical Sciences, 2011 Beta-tricalcium phosphate (β-TCP) has been used for bone regeneration with satisfactory clinical results in accelerating bone formation. However, little is known about the molecular mechanisms enhancing the bone formation by β-TCP. To understand this mechanism, β-TCP was implanted into bone defects of the mandible in beagles and gene expression ...
Cheng-Hsing Chu +6 more
openaire +2 more sources
Pericytes in Brain Homeostasis: Developmental Roles and Adult Functions
Frontiers in Bioscience-LandmarkPericytes (PCs) are multifunctional mural cells embedded in the basement membrane of microvessels and play essential roles in the development and maintenance of the central nervous system.
Uliana Drozd +2 more
doaj +1 more source
Hepatic stellate cells and parasite-induced liver fibrosis [PDF]
, 2010 : Fibrogenesis is a common feature of many diseases where there is severe insult to the liver. The hepatic stellate cell trans-differentiation into a myofibroblast has been identified as an important event in liver fibrogenesis and has been well ...
Allen, JT +3 more
core +2 more sources
Sorafenib for the treatment of unresectable hepatocellular carcinoma
Biologics: Targets & Therapy, 2008 Junji FuruseDepartment of Internal Medicine, Medical Oncology, School of Medicine, Kyorin UniversityAbstract: Raf kinases and vascular endothelial growth factor receptor (VEGFR) and platelet-derived growth factor receptor (PDGFR) tyrosine kinases are ...
Junji Furuse
doaj
Inducers of epithelial mesenchymal transition and cancer stem cells in malignant pleural effusions [PDF]
, 2016 The Epithelial to Mesenchymal Transition (EMT) plays a role not only in tumor metastasis but also in tumor recurrence. This process is believed to be tightly linked to the presence of Cancer Stem Cells (CSCs) however, it is still not clear which ...
Cherubini, Emanuela +5 more
core +1 more source