Results 81 to 90 of about 214,894 (274)
Heterogeneous and rate-dependent streptavidin-biotin unbinding revealed by high-speed force spectroscopy and atomistic simulations [PDF]
, 2019 Receptor-ligand interactions are essential for biological function and their binding strength is commonly explained in terms of static lock-and-key models based on molecular complementarity.
Gonzalez, Laura +4 more
core +4 more sources
Metal Nanoclusters for Cancer Imaging and Treatment
Advanced Functional Materials, EarlyView.This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu +5 more
wiley +1 more source
Scientific Reports, 2018 Tumor necrosis factor is a major pro-inflammatory cytokine which triggers various physiological consequences by binding to and trimerizing its receptors, and has been the single most sought-after drug target for intervening autoimmune diseases such as ...
Xiaofang Cui +9 more
doaj +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Design of High-Specificity Nanocarriers by Exploiting Non-Equilibrium Effects in Cancer Cell Targeting. [PDF]
PLoS ONE, 2013 Although targeting of cancer cells using drug-delivering nanocarriers holds promise for improving therapeutic agent specificity, the strategy of maximizing ligand affinity for receptors overexpressed on cancer cells is suboptimal.
Konstantinos Tsekouras +4 more
doaj +1 more source
Release of Soluble Ligands for the Activating NKG2D Receptor: One More Immune Evasion Strategy Evolved by HIV-1? [PDF]
, 2016 ncreasing lines of evidence indicate that NKG2D, an activating receptor of natural killer (NK) and CD8(+) T cells, plays an important role in immune responses against HIV-1. Through its ability to recognize a diverse array of ligands (NKG2DLs) induced by
Cerboni, Cristina +3 more
core +1 more source
Advanced Functional Materials, EarlyView.An alginate‐based biochar hydrogel (ABC‐hydrogel), derived from sewage sludge, is developed for simultaneous phosphate removal and agricultural reuse. It captures phosphorus from water and gradually releases it as fertilizer, enhancing lettuce growth.
Yu Zhang +4 more
wiley +1 more source
Role of cross-cleft contacts in NMDA receptor gating.
PLoS ONE, 2013 In response to brief glutamate exposure, NMDA receptors produce excitatory currents that have sub-maximal amplitudes and characteristically slow kinetics.
Meaghan A Paganelli +2 more
doaj +1 more source
Toward the 3rd Generation of Smart Farming: Materials, Devices, and Systems for E‐Plant Technologies
Advanced Functional Materials, EarlyView.This review explores the latest developments in e‐plant technologies, which are revolutionizing smart farming by enabling real‐time monitoring of plant and environmental conditions. It covers the design, applications, and systems of e‐plant devices, detailing how they integrate data analytics to optimize agricultural practices, enhance crop yields, and
Daegun Kim +5 more
wiley +1 more source
Advanced Functional Materials, EarlyView.This review describes the different surface engineering strategies for quantum dots that addresses the challenges associated with surface defects, highlighting their role in enhancing the performance of solar energy conversion technologies. Abstract Colloidal quantum dots (QDs) have garnered significant attention for their unique potential in clean ...
Kokilavani S., Gurpreet Singh Selopal
wiley +1 more source