Results 161 to 170 of about 220,108 (349)

Receptor-mediated endocytosis of ovalbumin by two carbohydrate-specific receptors in rat liver cells. The intracellular transport of ovalbumin to lysosomes is faster in liver endothelial cells than in parenchymal cells [PDF]

, 1990
Grete M. Kindberg, Sigurdur Magnusson, Trond Berg, Bård Smedsrød   +3 more
openalex   +1 more source

Rational Design of Metal–Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy

Advanced Materials, EarlyView.
This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle, Dhruv Menon, João Conniot, Jon Ostolaza‐Paraiso, Sergio Mercado, Jhenifer Oliveira, Xu Chen, Bárbara B. Mendes, João Conde, David Fairen‐Jimenez   +9 more
wiley   +1 more source

State‐of‐the‐Art, Insights, and Perspectives for MOFs‐Nanocomposites and MOF‐Derived (Nano)Materials

Advanced Materials, EarlyView.
Different approaches to MOF‐NP composite formation, such as ship‐in‐a‐bottle, bottle‐around‐the‐ship and in situ one‐step synthesis, are used. Owing to synergistic effects, the advantageous features of the components of the composites are beneficially combined, and their individual drawbacks are mitigated.
Stefanos Mourdikoudis, Subhajit Dutta, Saqib Kamal, Sergio Gómez‐Graña, Isabel Pastoriza‐Santos, Stefan Wuttke, Lakshminarayana Polavarapu   +6 more
wiley   +1 more source

Receptor-mediated endocytosis 8 (RME-8)/DNAJC13 is a novel positive modulator of autophagy and stabilizes cellular protein homeostasis. [PDF]

Cell Mol Life Sci, 2021
Besemer AS, Maus J, Ax MDA, Stein A, Vo S, Freese C, Nalbach K, von Hilchen C, Pfalzgraf IF, Koziollek-Drechsler I, Silva B, Huesmann H, Boukhallouk F, Florin L, Kern A, Behl C, Clement AM.   +16 more
europepmc   +1 more source

Selective Lipolysis by Photoactivation of Chaperone‐Mediated Autophagy Using Adipocyte Membrane‐Coated Nanoparticle in Hydrogel

Advanced Materials, EarlyView.
Adipocyte membrane‐coated nanoparticles loaded with rosiglitazone in hydrogel offer an alternative approach to conventional obesity treatments. This system selectively targets adipocytes, inducing lipolysis by activating chaperone‐mediated autophagy through mild photothermal stimulation.
Jaehyun Choi, Junho Byun, Dongyoon Kim, Qiaoyun Li, Dongun Jin, Yeong‐jin Choi, Ho Sang Jung, Jaiwoo Lee, Yu‐Kyoung Oh   +8 more
wiley   +1 more source

Receptor-mediated Endocytosis in theCaenorhabditis elegansOocyte [PDF]

, 1999
Barth D. Grant, David Hirsh
openalex   +1 more source

Mitochondrial Transplantation via Magnetically Responsive Artificial Cells Promotes Intracerebral Hemorrhage Recovery by Supporting Microglia Immunological Homeostasis

Advanced Materials, Volume 37, Issue 13, April 2, 2025.
A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou, Jinhui Zang, Yuxuan Qian, Qiang Zhang, Yifan Wang, Tingting Yao, Hongyu Yan, Kai Zhang, Xiaojun Cai, Lixian Jiang, Yuanyi Zheng   +10 more
wiley   +1 more source

Fcgamma receptor-mediated phagocytosis in macrophages lacking the Src family tyrosine kinases Hck, Fgr, and Lyn. [PDF]

, 2000
Macrophage Fcgamma receptors (FcgammaRs) mediate the uptake and destruction of antibody-coated viruses, bacteria, and parasites. We examined FcgammaR signaling and phagocytic function in bone marrow-derived macrophages from mutant mice lacking the major ...
Crowley, MT, DeFranco, AL, Finn, AJ, Fitzer-Attas, CJ, Lowell, CA, Lowry, M, Meng, F   +6 more
core  

Advanced glycation end products are eliminated by scavenger-receptor-mediated endocytosis in hepatic sinusoidal Kupffer and endothelial cells [PDF]

, 1997
Bård Smedsrød, Jukka Melkko, Norie Araki, Hiroyuki Sano, Seikoh Horiuchi   +4 more
openalex   +1 more source

The Rise of Mechanobiology for Advanced Cell Engineering and Manufacturing

Advanced Materials, EarlyView.
With the growing demand for cell‐based therapies, efficient cellular engineering is crucial. This review calls for greater recognition of mechanobiology principles applied through advanced biomaterial designs, mechanical confinement, and highlights recent advances using micro/nanotechnologies to enhance cell manufacturing.
Huan Ting Ong, M Sriram, Hepi Hari Susapto, Yixuan Li, Yuan Jiang, Nicolas H. Voelcker, Jennifer L. Young, Andrew W. Holle, Roey Elnathan   +8 more
wiley   +1 more source