Results 181 to 190 of about 220,108 (349)

Reengineering Endogenous Targeting Lipid Nanoparticles (ENDO) for Systemic Delivery of mRNA to Pancreas

Advanced Materials, EarlyView.
ENDO lipid nanoparticles containing cholecalciferol as a fifth component demonstrate mRNA delivery to the pancreas with 99% selectivity, including beta cells. This platform shows minimal toxicity and sustained protein expression for up to 3 days in a dose‐dependent manner, offering a novel approach to pancreas‐specific mRNA delivery and gene therapy ...
Ivan Isaac, Luv Patel, Nguyen Tran, Amarnath Singam, DongSoo Yun, Prasun Guha, Seungman Park, Chandrabali Bhattacharya   +7 more
wiley   +1 more source

Nanostructured Protein Surfaces Inspired by Spider Silk

Advanced Materials, EarlyView.
Harnessing recombinant spider silk technology, bioengineered spidroin variants enable the creation of functionalized nanostructured coatings with tunable affinity for specific targets, supporting a broad range of applications ‐ from antifouling surfaces and targeted drug delivery to advanced cell therapies and precision bio‐patterning via lithography ...
Martin Humenik, Thomas Scheibel
wiley   +1 more source

Albondin-mediated capillary permeability to albumin. Differential role of receptors in endothelial transcytosis and endocytosis of native and modified albumins.

, 1994
Jan E. Schnitzer, Philmo Oh
openalex   +1 more source

Fcα/μ receptor mediates endocytosis of IgM-coated microbes [PDF]

, 2000
Akira Shibuya, Norihisa Sakamoto, Yoshio Shimizu, Kazuko Shibuya, Mitsujiro Osawa, Takashi Hiroyama, Helen J. Eyre, Grant R. Sutherland, Yuichi Endo, Teizo Fujita, Tomoyuki Miyabayashi, Seiji Sakano, Takao Tsuji, Eiichi Nakayama, Joseph H. Phillips, Lewis L. Lanier, Hiromitsu Nakauchi   +16 more
openalex   +1 more source

Advances and Strategies in Enhancing mRNA Cancer Vaccines

Advanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang, Shengqi Chen, Haijun Hu, Yenhui Ong, Qianqian Ni   +4 more
wiley   +1 more source

Clathrin couture: Fashioning distinctive membrane coats at the cell surface [PDF]

, 2009
B. M Collins, B. T Kelly, C Raiborg, C. J Merrifield, D Leonard, D Loerke, D. A Sanan, D. K Cureton, E Boucrot, E. M Schmid, F. Z Idrissi, I Gaidarov, J Barroso-Gonzalez, J Heuser, J Heuser, J Rosenbluth, J. Z Rappoport, J. Z Rappoport, K Miller, K. D Bellve, L Hinrichsen, Linton M. Traub, M Ehrlich, M Kaksonen, M Lakadamyali, M. A Puthenveedu, M. C Saleh, N Abe, P Maupin, P Varnai, P. A Keyel, P. A Keyel, R Zoncu, S Mayor, S Saffarian, S. J Mundell, T Akisaka, T Ben-Kasus, T Kirchhausen, T. A Gottlieb, T. F Roth, X Wu   +41 more
core   +4 more sources

Mice lacking renal chloride channel, CLC-5, are a model for Dent's disease, a nephrolithiasis disorder associated with defective receptor-mediated endocytosis [PDF]

, 2000
Sophia Wang
openalex   +1 more source

Biomolecular Condensates as Emerging Biomaterials: Functional Mechanisms and Advances in Computational and Experimental Approaches

Advanced Materials, EarlyView.
Integration of computational and experimental approaches for deciphering the underlying mechanism of biomolecular condensates and potential biomaterials design (Created in Biorender. Raza, Z. (2025) https://BioRender.com/irgmeqi). Abstract Biomolecular condensates, a ubiquitous class of biomaterials found in living cells, have been shown to be ...
Qiang Zhu, Zahra Raza, Dzung Do‐Ha, Emma De Costa, Pavlina Sasheva, Luke McAlary, Hadi Mahmodi, Warwick P. Bowen, Lezanne Ooi, Irina Kabakova, Haibo Yu   +10 more
wiley   +1 more source

Receptor-mediated gene transfer to airway epithelial cells in primary culture [PDF]

, 1993
Agarwal, Santosh, Curiel, David T., Harris, C. E., Hu, P.-C., Wagner, Ernst   +4 more
core   +1 more source

end3 and end4: two mutants defective in receptor-mediated and fluid-phase endocytosis in Saccharomyces cerevisiae.

, 1993
Susan Raths, Jack Rohrer, Fabienne Crausaz, Howard Riezman   +3 more
openalex   +1 more source